Literature DB >> 20518085

Heme oxygenase-1 system and gastrointestinal tumors.

Xiao Zhu1, Wen-Guo Fan, Dong-Pei Li, Marie C M Lin, Hsiangfu Kung.   

Abstract

Heme oxygenase-1 (HO-1) system catabolizes heme into three products: carbon monoxide, biliverdin/bilirubin and free iron. It is involved in many physiological and pathophysiological processes. A great deal of data has demonstrated the roles of HO-1 in the formation, growth and metastasis of tumors. The interest in this system by investigators involved in gastrointestinal tumors is fairly recent, and few papers on HO-1 have touched upon this subject. This review focuses on the current understanding of the physiological significance of HO-1 induction and its possible roles in the gastrointestinal tumors studied to date. The implications for possible therapeutic manipulation of HO-1 in gastrointestinal tumors are also discussed.

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Year:  2010        PMID： 20518085      PMCID： PMC2880776          DOI： 10.3748/wjg.v16.i21.2633

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN： 1007-9327            Impact factor:   5.742


  55 in total

1.  Development of a survival evaluation model for liver transplant recipients with hepatocellular carcinoma secondary to hepatitis B.

Authors:  Ming Zhang; Bo Li; Lu-Nan Yan; Fei Yin; Tian-Fu Wen; Yong Zeng; Ji-Chun Zhao; Yu-Kui Ma
Journal:  World J Gastroenterol       Date:  2008-02-28       Impact factor: 5.742

2.  Haeme oxygenase-1 promoter polymorphism is an independent prognostic marker of gastrointestinal stromal tumour.

Authors:  Yogesh K Vashist; Guentac Uzunoglu; Guelle Cataldegirmen; Viacheslar Kalinin; Paulus Schurr; Alexandra M Koenig; Sabrina Thieltges; Oliver Zehler; Claus Schneider; Jacob R Izbicki; Emre F Yekebas
Journal:  Histopathology       Date:  2009-02       Impact factor: 5.087

3.  Heme oxygenase-1 induction by hemin protects liver cells from ischemia/reperfusion injury in cirrhotic rats.

Authors:  Hui Xue; Hua Guo; Ying-Chao Li; Zhi-Ming Hao
Journal:  World J Gastroenterol       Date:  2007-10-28       Impact factor: 5.742

4.  The dimethylthiourea-induced attenuation of cisplatin nephrotoxicity is associated with the augmented induction of heat shock proteins.

Authors:  Takayuki Tsuji; Akihiko Kato; Hideo Yasuda; Takehiko Miyaji; Jinghui Luo; Yukitoshi Sakao; Hideaki Ito; Yoshihide Fujigaki; Akira Hishida
Journal:  Toxicol Appl Pharmacol       Date:  2008-10-18       Impact factor: 4.219

5.  Inhibition of heme oxygenase 1 expression by small interfering RNA decreases orthotopic tumor growth in livers of mice.

Authors:  Gabriele Sass; Petra Leukel; Volker Schmitz; Esther Raskopf; Matthias Ocker; Daniel Neureiter; Matthias Meissnitzer; Elena Tasika; Andrea Tannapfel; Gisa Tiegs
Journal:  Int J Cancer       Date:  2008-09-15       Impact factor: 7.396

Review 6.  Heme oxygenase-1 in tumors: is it a false friend?

Authors:  Alicja Jozkowicz; Halina Was; Jozef Dulak
Journal:  Antioxid Redox Signal       Date:  2007-12       Impact factor: 8.401

7.  Upregulation of heme oxygenase-1 in oral epithelial dysplasias.

Authors:  J Lee; S-K Lee; B-U Lee; H-J Lee; N-P Cho; J-H Yoon; H-R Choi; S-K Lee; E-C Kim
Journal:  Int J Oral Maxillofac Surg       Date:  2008-02-12       Impact factor: 2.789

8.  Prevention of hemorrhagic shock-induced intestinal tissue injury by glutamine via heme oxygenase-1 induction.

Authors:  Kana Umeda; Toru Takahashi; Kazuyoshi Inoue; Hiroko Shimizu; Shigeru Maeda; Hiroshi Morimatsu; Emiko Omori; Reiko Akagi; Hiroshi Katayama; Kiyoshi Morita
Journal:  Shock       Date:  2009-01       Impact factor: 3.454

9.  Increased risk of gastric cancer in Japanese subjects is associated with microsatellite polymorphisms in the heme oxygenase-1 and the inducible nitric oxide synthase gene promoters.

Authors:  Tomohiro Sawa; Mounia Mounawar; Masayuki Tatemichi; Isabelle Gilibert; Takahiko Katoh; Hiroshi Ohshima
Journal:  Cancer Lett       Date:  2008-05-27       Impact factor: 8.679

10.  Zerumbone, a tropical ginger sesquiterpene, inhibits colon and lung carcinogenesis in mice.

Authors:  Mihye Kim; Shingo Miyamoto; Yumiko Yasui; Takeru Oyama; Akira Murakami; Takuji Tanaka
Journal:  Int J Cancer       Date:  2009-01-15       Impact factor: 7.396
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  10 in total

1.  Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations.

Authors:  Chen Wu; Xiaoping Miao; Liming Huang; Xu Che; Guoliang Jiang; Dianke Yu; Xianghong Yang; Guangwen Cao; Zhibin Hu; Yongjian Zhou; Chaohui Zuo; Chunyou Wang; Xianghong Zhang; Yifeng Zhou; Xianjun Yu; Wanjin Dai; Zhaoshen Li; Hongbing Shen; Luming Liu; Yanling Chen; Sheng Zhang; Xiaoqi Wang; Kan Zhai; Jiang Chang; Yu Liu; Menghong Sun; Wei Cao; Jun Gao; Ying Ma; Xiongwei Zheng; Siu Tim Cheung; Yongfeng Jia; Jian Xu; Wen Tan; Ping Zhao; Tangchun Wu; Chengfeng Wang; Dongxin Lin
Journal:  Nat Genet       Date:  2011-12-11       Impact factor: 38.330

Review 2.  Heme oxygenase-1 system and gastrointestinal inflammation: a short review.

Authors:  Xiao Zhu; Wen-Guo Fan; Dong-Pei Li; Hsiangfu Kung; Marie Cm Lin
Journal:  World J Gastroenterol       Date:  2011-10-14       Impact factor: 5.742

3.  Association between GT-repeat polymorphism at heme oxygenase-1 gene promoter and gastric cancer and metastasis.

Authors:  M Motovali-Bashi; M Hamidy
Journal:  Tumour Biol       Date:  2015-05-10

4.  Consumption of vitamin B6 reduces colonic damage and protein expression of HSP70 and HO-1, the anti-tumor targets, in rats exposed to 1,2-dimethylhydrazine.

Authors:  Tomoko Kayashima; Kenta Tanaka; Yukako Okazaki; Kiminori Matsubara; Noriyuki Yanaka; Norihisa Kato
Journal:  Oncol Lett       Date:  2011-08-02       Impact factor: 2.967

5.  Radical decisions in cancer: redox control of cell growth and death.

Authors:  Rosa M Sainz; Felipe Lombo; Juan C Mayo
Journal:  Cancers (Basel)       Date:  2012-04-25       Impact factor: 6.639

6.  Heme oxygenase 1 facilitates cell proliferation via the B-Raf-ERK signaling pathway in melanoma.

Authors:  Liu Liu; Yan Wu; Chunxiang Bian; Muhammad Farrukh Nisar; Mei Wang; Xiangyu Hu; Qingchun Diao; Weiqi Nian; Enwen Wang; Wei Xu; Julia Li Zhong
Journal:  Cell Commun Signal       Date:  2019-01-11       Impact factor: 5.712

Review 7.  The Mechanisms of Ferroptosis and the Applications in Tumor Treatment: Enemies or Friends?

Authors:  Shuzheng Tan; Ying Kong; Yongtong Xian; Pengbo Gao; Yue Xu; Chuzhong Wei; Peixu Lin; Weilong Ye; Zesong Li; Xiao Zhu
Journal:  Front Mol Biosci       Date:  2022-07-15

8.  Functional role of BTB and CNC Homology 1 gene in pancreatic cancer and its association with survival in patients treated with gemcitabine.

Authors:  Xudong Huang; Jian Zheng; Jun Li; Xu Che; Wenle Tan; Wen Tan; Mingming Shao; Xinxin Cheng; Zhongli Du; Yanjie Zhao; Chengfeng Wang; Chen Wu; Dongxin Lin
Journal:  Theranostics       Date:  2018-05-23       Impact factor: 11.556

9.  Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent In Vitro Antiproliferative Activity.

Authors:  Antonino N Fallica; Valeria Sorrenti; Agata G D'Amico; Loredana Salerno; Giuseppe Romeo; Sebastiano Intagliata; Valeria Consoli; Giuseppe Floresta; Antonio Rescifina; Velia D'Agata; Luca Vanella; Valeria Pittalà
Journal:  J Med Chem       Date:  2021-09-02       Impact factor: 7.446

Review 10.  New insights into molecules and pathways of cancer metabolism and therapeutic implications.

Authors:  Zhenye Tang; Zhenhua Xu; Xiao Zhu; Jinfang Zhang
Journal:  Cancer Commun (Lond)       Date:  2020-11-10
  10 in total

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