PURPOSE: The goal of this study was to estimate pre- and post-gadolinium-enhanced high-spatial resolution susceptibility-weighted imaging (SWI) in patients with brain neoplasms. MATERIALS AND METHODS: A total of 17 patients (8 women, 9 men) with brain neoplasms participated in this study. In addition to conventional magnetic resonance imaging, pre- and post-gadolinium-enhanced SWI was performed. The contrast-to-noise ratio (CNR) and major diameters of the brain tumor were measured for quantitative analyses, and intratumoral susceptibility signal intensity (ITSS) was graded for semiquantitative analysis. RESULTS: Both bright and dark enhancement were observed at the pathological lesion on postcontrast SWI. Some postcontrast SWI results suggested leakage of contrast material due to breakdown of the blood-brain barrier. There were no statistical differences (Student's t-test) between postcontrast SWI and three-dimensional (3D) T1-weighted images regarding the major diameters of the brain tumors. CNR of postcontrast 3D T1-weighted images was statistically superior to that of postcontrast SW images (P < 0.01, Wilcoxon signed-rank test). Malignant tumors tended to have a higher ITSS score. CONCLUSION: SWI clearly visualized the architecture of brain neoplasms. This imaging technique may be useful for evaluating tumor characterization in clinical use.
PURPOSE: The goal of this study was to estimate pre- and post-gadolinium-enhanced high-spatial resolution susceptibility-weighted imaging (SWI) in patients with brain neoplasms. MATERIALS AND METHODS: A total of 17 patients (8 women, 9 men) with brain neoplasms participated in this study. In addition to conventional magnetic resonance imaging, pre- and post-gadolinium-enhanced SWI was performed. The contrast-to-noise ratio (CNR) and major diameters of the brain tumor were measured for quantitative analyses, and intratumoral susceptibility signal intensity (ITSS) was graded for semiquantitative analysis. RESULTS: Both bright and dark enhancement were observed at the pathological lesion on postcontrast SWI. Some postcontrast SWI results suggested leakage of contrast material due to breakdown of the blood-brain barrier. There were no statistical differences (Student's t-test) between postcontrast SWI and three-dimensional (3D) T1-weighted images regarding the major diameters of the brain tumors. CNR of postcontrast 3D T1-weighted images was statistically superior to that of postcontrast SW images (P < 0.01, Wilcoxon signed-rank test). Malignant tumors tended to have a higher ITSS score. CONCLUSION: SWI clearly visualized the architecture of brain neoplasms. This imaging technique may be useful for evaluating tumor characterization in clinical use.
Authors: Vivek Sehgal; Zachary Delproposto; E Mark Haacke; Karen A Tong; Nathaniel Wycliffe; Daniel K Kido; Yingbiao Xu; Jaladhar Neelavalli; Djamel Haddar; Jürgen R Reichenbach Journal: J Magn Reson Imaging Date: 2005-10 Impact factor: 4.813
Authors: Alexander Rauscher; Jan Sedlacik; Markus Barth; E Mark Haacke; Jürgen R Reichenbach Journal: Magn Reson Med Date: 2005-07 Impact factor: 4.668
Authors: K Pinker; I M Noebauer-Huhmann; I Stavrou; R Hoeftberger; P Szomolanyi; G Karanikas; M Weber; A Stadlbauer; E Knosp; K Friedrich; S Trattnig Journal: AJNR Am J Neuroradiol Date: 2007-08 Impact factor: 3.825
Authors: Alexander Rauscher; Jan Sedlacik; Markus Barth; Hans-Joachim Mentzel; Jürgen R Reichenbach Journal: AJNR Am J Neuroradiol Date: 2005-04 Impact factor: 3.825
Authors: K Pinker; I M Noebauer-Huhmann; I Stavrou; R Hoeftberger; P Szomolanyi; M Weber; A Stadlbauer; G Grabner; E Knosp; S Trattnig Journal: Neuroradiology Date: 2007-09-18 Impact factor: 2.804
Authors: Delia Fahrendorf; Wolfram Schwindt; Johannes Wölfer; Astrid Jeibmann; Hendrik Kooijman; Harald Kugel; Oliver Grauer; Walter Heindel; Volker Hesselmann; Andrea Bink Journal: Eur Radiol Date: 2013-08-01 Impact factor: 5.315
Authors: Chris Albanese; Olga C Rodriguez; John VanMeter; Stanley T Fricke; Brian R Rood; YiChien Lee; Sean S Wang; Subha Madhavan; Yuriy Gusev; Emanuel F Petricoin; Yue Wang Journal: Am J Pathol Date: 2012-12-04 Impact factor: 4.307
Authors: Julia Wieczorek-Pastusiak; Marek Kociński; Marek Raźniewski; Michał Strzelecki; Ludomir Stefańczyk; Agata Majos Journal: Pol J Radiol Date: 2013-01