Literature DB >> 20509131

Design and folding of [GluA4(ObetaThrB30)]insulin ("ester insulin"): a minimal proinsulin surrogate that can be chemically converted into human insulin.

Youhei Sohma1, Qing-Xin Hua, Jonathan Whittaker, Michael A Weiss, Stephen B H Kent.   

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Year:  2010        PMID： 20509131      PMCID： PMC3311283          DOI： 10.1002/anie.201001151

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  27 in total

Review 1.  Large-scale manufacture of peptide therapeutics by chemical synthesis.

Authors:  Brian L Bray
Journal:  Nat Rev Drug Discov       Date:  2003-07       Impact factor: 84.694

2.  Studies on human proinsulin. Isolation and amino acid sequence of the human pancreatic C-peptide.

Authors:  P E Oyer; S Cho; J D Peterson; D F Steiner
Journal:  J Biol Chem       Date:  1971-03-10       Impact factor: 5.157

3.  [Total synthesis of human insulin. IV. Description of the final steps (author's transl)].

Authors:  P Sieber; B Kamber; A Hartmann; A Jöhl; B Riniker; W Rittel
Journal:  Helv Chim Acta       Date:  1977-01-26       Impact factor: 2.164

4.  Two routes for producing human insulin utilizing recombinant DNA technology.

Authors:  B H Frank; R E Chance
Journal:  MMW Munch Med Wochenschr       Date:  1983-05-04

5.  The synthesis of bovine insulin by the solid phase method.

Authors:  A Marglin; R B Merrifield
Journal:  J Am Chem Soc       Date:  1966-11-05       Impact factor: 15.419

6.  Renaturation of human proinsulin--a study on refolding and conversion to insulin.

Authors:  Jeannette Winter; Hauke Lilie; Rainer Rudolph
Journal:  Anal Biochem       Date:  2002-11-15       Impact factor: 3.365

7.  Secretion and processing of insulin precursors in yeast.

Authors:  L Thim; M T Hansen; K Norris; I Hoegh; E Boel; J Forstrom; G Ammerer; N P Fiil
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

8.  Single chain des-(B30) insulin. Intramolecular crosslinking of insulin by trypsin catalyzed transpeptidation.

Authors:  J Markussen; K H Jørgensen; A R Sørensen; L Thim
Journal:  Int J Pept Protein Res       Date:  1985-07

9.  Perturbation of insulin-receptor interactions by intramolecular hormone cross-linking. Analysis of relative movement among residues A1, B1, and B29.

Authors:  S H Nakagawa; H S Tager
Journal:  J Biol Chem       Date:  1989-01-05       Impact factor: 5.157

10.  Mechanism of insulin chain combination. Asymmetric roles of A-chain alpha-helices in disulfide pairing.

Authors:  Qing-Xin Hua; Ying-Chi Chu; Wenhua Jia; Nelson F B Phillips; Run-Ying Wang; Panayotis G Katsoyannis; Michael A Weiss
Journal:  J Biol Chem       Date:  2002-08-23       Impact factor: 5.157
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  11 in total

Review 1.  General lack of structural characterization of chemically synthesized long peptides.

Authors:  Jean A Boutin; André L Tartar; Alain van Dorsselaer; Hubert Vaudry
Journal:  Protein Sci       Date:  2019-03-25       Impact factor: 6.725

Review 2.  Novel protein science enabled by total chemical synthesis.

Authors:  Stephen B H Kent
Journal:  Protein Sci       Date:  2018-12-18       Impact factor: 6.725

3.  Fully convergent chemical synthesis of ester insulin: determination of the high resolution X-ray structure by racemic protein crystallography.

Authors:  Michal Avital-Shmilovici; Kalyaneswar Mandal; Zachary P Gates; Nelson B Phillips; Michael A Weiss; Stephen B H Kent
Journal:  J Am Chem Soc       Date:  2013-02-08       Impact factor: 15.419

Review 4.  Pursuit of a perfect insulin.

Authors:  Alexander N Zaykov; John P Mayer; Richard D DiMarchi
Journal:  Nat Rev Drug Discov       Date:  2016-03-18       Impact factor: 84.694

5.  Efficient Total Chemical Synthesis of (13) C=(18) O Isotopomers of Human Insulin for Isotope-Edited FTIR.

Authors:  Balamurugan Dhayalan; Ann Fitzpatrick; Kalyaneswar Mandal; Jonathan Whittaker; Michael A Weiss; Andrei Tokmakoff; Stephen B H Kent
Journal:  Chembiochem       Date:  2016-02-16       Impact factor: 3.164

6.  Chemically Precise Glycoengineering Improves Human Insulin.

Authors:  Xiaoyang Guan; Patrick K Chaffey; Xiuli Wei; Daniel R Gulbranson; Yuan Ruan; Xinfeng Wang; Yaohao Li; Yan Ouyang; Liqun Chen; Chen Zeng; Theo N Koelsch; Amy H Tran; Wei Liang; Jingshi Shen; Zhongping Tan
Journal:  ACS Chem Biol       Date:  2017-12-01       Impact factor: 5.100

7.  Substitution of an Internal Disulfide Bridge with a Diselenide Enhances both Foldability and Stability of Human Insulin.

Authors:  Orit Weil-Ktorza; Nischay Rege; Shifra Lansky; Deborah E Shalev; Gil Shoham; Michael A Weiss; Norman Metanis
Journal:  Chemistry       Date:  2019-05-16       Impact factor: 5.236

8.  Scope and Limitations of Fmoc Chemistry SPPS-Based Approaches to the Total Synthesis of Insulin Lispro via Ester Insulin.

Authors:  Balamurugan Dhayalan; Kalyaneswar Mandal; Nischay Rege; Michael A Weiss; Simon H Eitel; Thomas Meier; Ralph O Schoenleber; Stephen B H Kent
Journal:  Chemistry       Date:  2017-01-10       Impact factor: 5.020

9.  Total chemical synthesis of ester-linked ubiquitinated proteins unravels their behavior with deubiquitinases.

Authors:  Hao Sun; Roman Meledin; Sachitanand M Mali; Ashraf Brik
Journal:  Chem Sci       Date:  2018-01-11       Impact factor: 9.825

10.  Facile folding of insulin variants bearing a prosthetic C-peptide prepared by α-ketoacid-hydroxylamine (KAHA) ligation.

Authors:  Gábor N Boross; Satomi Shimura; Melissa Besenius; Norbert Tennagels; Kai Rossen; Michael Wagner; Jeffrey W Bode
Journal:  Chem Sci       Date:  2018-09-11       Impact factor: 9.825
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