Literature DB >> 2050206

Effects of ceftriaxone on faecal flora: analysis by micromorphometry.

B C Meijer1, G J Kootstra, D G Geertsma, M H Wilkinson.   

Abstract

In order to elucidate the effect of ceftriaxone therapy on the morphology of gut microflora, 11 human volunteers were treated with ceftriaxone, 1 g daily, given intramuscularly in one dose. Treatment continued for 5 days. Faecal microflora was analysed by digital image processing before, during and after the treatment period. We derived simple numerical parameters which describe the morphologic composition of the flora. They were significantly influenced by the antibiotic, and returned to their baseline values more than 7 days after treatment was stopped. The procedure holds promise for clinical application.

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Year:  1991        PMID： 2050206      PMCID： PMC2271876          DOI： 10.1017/s0950268800067571

Source DB:  PubMed          Journal:  Epidemiol Infect        ISSN： 0950-2688            Impact factor:   2.451


  9 in total

1.  Rapid enumeration of viable bacteria by image analysis.

Authors:  A Singh; B H Pyle; G A McFeters
Journal:  J Microbiol Methods       Date:  1989       Impact factor: 2.363

2.  Effect of amoxicillin-clavulanate and cephradine on the fecal flora of healthy volunteers not exposed to a hospital environment.

Authors:  W Brumfitt; I Franklin; D Grady; J M Hamilton-Miller
Journal:  Antimicrob Agents Chemother       Date:  1986-08       Impact factor: 5.191

Review 3.  Applications of computerized microscopic image analysis in infectious diseases.

Authors:  E Goldstein; R M Donovan; Y Kim
Journal:  Rev Infect Dis       Date:  1988 Jan-Feb

4.  Colonization resistance of the digestive tract in conventional and antibiotic-treated mice.

Authors:  D van der Waaij; J M Berghuis-de Vries
Journal:  J Hyg (Lond)       Date:  1971-09

5.  The effect of new broad-spectrum antibiotics on faecal flora of cancer patients.

Authors:  G J Meijer-Severs; J H Joshi
Journal:  J Antimicrob Chemother       Date:  1989-10       Impact factor: 5.790

6.  Impact of ticarcillin/clavulanate on the intestinal microflora.

Authors:  C E Nord; T Bergan; S B Thorsteinsson
Journal:  J Antimicrob Chemother       Date:  1989-11       Impact factor: 5.790

7.  The influence of single dose intravenous antibiotics on faecal flora and emergence of Clostridium difficile.

Authors:  N S Ambrose; M Johnson; D W Burdon; M R Keighley
Journal:  J Antimicrob Chemother       Date:  1985-03       Impact factor: 5.790

8.  Influence of oral intake of seven different antibiotics on faecal short-chain fatty acid excretion in healthy subjects.

Authors:  T Høverstad; B Carlstedt-Duke; E Lingaas; E Norin; H Saxerholt; M Steinbakk; T Midtvedt
Journal:  Scand J Gastroenterol       Date:  1986-10       Impact factor: 2.423

9.  Effect of moxalactam on human fecal microflora.

Authors:  Y Benno; N Shiragami; K Uchida; T Yoshida; T Mitsuoka
Journal:  Antimicrob Agents Chemother       Date:  1986-01       Impact factor: 5.191
  9 in total
  6 in total

1.  Micromorphometrical analysis of rodent related (SPF) and unrelated (human) gut microbial flora in germfree mice by digital image processing.

Authors:  D Veenendaal; J de Boer; B C Meijer; D van der Waaij; M H Wilkinson
Journal:  Epidemiol Infect       Date:  1996-02       Impact factor: 2.451

2.  Quantitative fluorescence in situ hybridization of Bifidobacterium spp. with genus-specific 16S rRNA-targeted probes and its application in fecal samples.

Authors:  P S Langendijk; F Schut; G J Jansen; G C Raangs; G R Kamphuis; M H Wilkinson; G W Welling
Journal:  Appl Environ Microbiol       Date:  1995-08       Impact factor: 4.792

3.  Characterization of human faecal flora by means of an improved fluoro-morphometrical method.

Authors:  G J Jansen; M H Wilkinson; B Deddens; D van der Waaij
Journal:  Epidemiol Infect       Date:  1993-10       Impact factor: 2.451

4.  Escherichia coli as a probiotic?

Authors:  G J Jansen; A C Wildeboer-Veloo; D van der Waaij; J E Degener
Journal:  Infection       Date:  1998 Jul-Aug       Impact factor: 3.553

5.  Healthy individuals possess circulating antibodies against their indigenous faecal microflora as well as against allogenous faecal microflora: an immunomorphometrical study.

Authors:  H Z Apperloo-Renkema; T G Jagt; R H Tonk; D van der Waaij
Journal:  Epidemiol Infect       Date:  1993-10       Impact factor: 2.451

6.  The influence of Enterococcus faecalis on the morphology and the antibody-binding capacity of the intestinal bacteria of ten healthy human volunteers.

Authors:  G Jansen; B Deddens; M Wilkinson; D van der Waaij
Journal:  Infection       Date:  1995 Jan-Feb       Impact factor: 3.553
  6 in total

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