PURPOSE: To evaluate the role of Anti-mullerian hormone (AMH) in predicting cumulative pregnancy outcome during in-vitro fertilization (IVF) treatment. METHODS: Serum AMH levels on day 6 of ovarian stimulation were taken from 180 women undergoing IVF with or without intracytoplasmic sperm injection (ICSI). The main outcome measures were ongoing pregnancy in the fresh cycle, cumulative ongoing pregnancy and ovarian response. RESULTS: There was a trend of higher median AMH levels in subjects achieving ongoing pregnancy in the fresh IVF cycle. The median AMH levels were significantly higher in subjects attaining ongoing pregnancy cumulatively and in subjects showing ovarian hyper-response in the stimulated cycle. Areas under the ROC curves were 0.606 and 0.792 for the prediction of cumulative ongoing pregnancy and ovarian hyper-response respectively. CONCLUSIONS: Serum AMH concentration on day 6 of stimulation was significantly higher in subjects who achieved cumulative ongoing pregnancy in IVF compared to those who did not. Serum AMH is a reasonably good predictor of ovarian hyper-response.
PURPOSE: To evaluate the role of Anti-mullerian hormone (AMH) in predicting cumulative pregnancy outcome during in-vitro fertilization (IVF) treatment. METHODS: Serum AMH levels on day 6 of ovarian stimulation were taken from 180 women undergoing IVF with or without intracytoplasmic sperm injection (ICSI). The main outcome measures were ongoing pregnancy in the fresh cycle, cumulative ongoing pregnancy and ovarian response. RESULTS: There was a trend of higher median AMH levels in subjects achieving ongoing pregnancy in the fresh IVF cycle. The median AMH levels were significantly higher in subjects attaining ongoing pregnancy cumulatively and in subjects showing ovarian hyper-response in the stimulated cycle. Areas under the ROC curves were 0.606 and 0.792 for the prediction of cumulative ongoing pregnancy and ovarian hyper-response respectively. CONCLUSIONS: Serum AMH concentration on day 6 of stimulation was significantly higher in subjects who achieved cumulative ongoing pregnancy in IVF compared to those who did not. Serum AMH is a reasonably good predictor of ovarian hyper-response.
Authors: Wouter J K Hehenkamp; Caspar W N Looman; Axel P N Themmen; Frank H de Jong; E R Te Velde; Frank J M Broekmans Journal: J Clin Endocrinol Metab Date: 2006-06-27 Impact factor: 5.958
Authors: Jesper M J Smeenk; Fred C G J Sweep; Gerhard A Zielhuis; Jan A M Kremer; Chris M G Thomas; Didi D M Braat Journal: Fertil Steril Date: 2006-11-01 Impact factor: 7.329
Authors: André Hazout; Philippe Bouchard; David B Seifer; P Aussage; Anne Marie Junca; Paul Cohen-Bacrie Journal: Fertil Steril Date: 2004-11 Impact factor: 7.329
Authors: Dharmawijaya N Lekamge; Michael Barry; Michele Kolo; Michelle Lane; Robert B Gilchrist; Kelton P Tremellen Journal: Reprod Biomed Online Date: 2007-05 Impact factor: 3.828
Authors: Hang Wun Raymond Li; Ernest Hung Yu Ng; Benancy Po Chau Wong; Richard A Anderson; Pak Chung Ho; William Shu Biu Yeung Journal: J Assist Reprod Genet Date: 2012-11-02 Impact factor: 3.412
Authors: Selma İnat Capkın; Sebnem Ozyer; Rana Karayalçın; Ozlem Moraloğlu; Sarp Ozcan; Mustafa Uğur Journal: J Turk Ger Gynecol Assoc Date: 2012-03-01
Authors: Hang Wun Raymond Li; Vivian Chi Yan Lee; Estella Yee Lan Lau; William Shu Biu Yeung; Pak Chung Ho; Ernest Hung Yu Ng Journal: PLoS One Date: 2013-04-23 Impact factor: 3.240