Literature DB >> 20466618

The role of the pathologist in rectal cancer diagnosis and staging and surgical quality assessment.

Carmen Faus1, Desamparados Roda, Matteo Frasson, Susana Roselló, Eduardo García-Granero, Blas Flor-Lorente, Samuel Navarro.   

Abstract

Since the introduction of the total mesorectal excision by Heald, many changes in the therapeutic management of rectal cancer have been incorporated. The multidisciplinary approach to colorectal cancer, integrated in a team of different specialists, ensures individualised treatment for each patient with rectal cancer. Therefore the role of the pathologist has acquired an important relevance, not only in diagnosing but also managing and evaluating the surgical specimen. The knowledge of preoperative staging, distance between tumour and anal verge or in patients subjected to a neoadjuvant treatment is necessary for the pathologist to make a detailed, accurate and good-quality report. Parameters such as the macroscopic quality of the mesorectum, the status of the circumferential resection margin and the lymph node harvest are considered basic criteria recommended by the current guidelines for the multidisciplinary team audit.

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Year:  2010        PMID: 20466618     DOI: 10.1007/s12094-010-0515-7

Source DB:  PubMed          Journal:  Clin Transl Oncol        ISSN: 1699-048X            Impact factor:   3.405


  60 in total

1.  Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer.

Authors:  E Kapiteijn; C A Marijnen; I D Nagtegaal; H Putter; W H Steup; T Wiggers; H J Rutten; L Pahlman; B Glimelius; J H van Krieken; J W Leer; C J van de Velde
Journal:  N Engl J Med       Date:  2001-08-30       Impact factor: 91.245

2.  Prognostic significance of radial margins of clearance in rectal cancer.

Authors:  D F de Haas-Kock; C G Baeten; J J Jager; J A Langendijk; L J Schouten; A Volovics; J W Arends
Journal:  Br J Surg       Date:  1996-06       Impact factor: 6.939

3.  Chances of cure are not compromised with sphincter-saving procedures for cancer of the lower third of the rectum.

Authors:  I C Lavery; F Lopez-Kostner; V W Fazio; M Fernandez-Martin; J W Milsom; J M Church
Journal:  Surgery       Date:  1997-10       Impact factor: 3.982

4.  Local recurrence following total mesorectal excision for rectal cancer.

Authors:  G Arbman; E Nilsson; O Hallböök; R Sjödahl
Journal:  Br J Surg       Date:  1996-03       Impact factor: 6.939

5.  Abdominoperineal excision of the rectum--an endangered operation. Norman Nigro Lectureship.

Authors:  R J Heald; R K Smedh; A Kald; R Sexton; B J Moran
Journal:  Dis Colon Rectum       Date:  1997-07       Impact factor: 4.585

6.  Rectal cancer: the Basingstoke experience of total mesorectal excision, 1978-1997.

Authors:  R J Heald; B J Moran; R D Ryall; R Sexton; J K MacFarlane
Journal:  Arch Surg       Date:  1998-08

7.  [Long-term results after surgery for colorectal adenocarcinoma, stage I-III. Problems of prognosis].

Authors:  St O Georgescu; C N Neacşu; D Vintilă; Paula Popa; Liliana Forţu; A Nistor; D Ferariu; E Târcoveanu
Journal:  Rev Med Chir Soc Med Nat Iasi       Date:  2007 Oct-Dec

8.  Prognostic value of tumor "budding" in patients with colorectal cancer.

Authors:  K Hase; C Shatney; D Johnson; M Trollope; M Vierra
Journal:  Dis Colon Rectum       Date:  1993-07       Impact factor: 4.585

9.  The influence of the number of retrieved lymph nodes on staging and survival in patients with stage II and III rectal cancer undergoing tumor-specific mesorectal excision.

Authors:  Young-Wan Kim; Nam-Kyu Kim; Byung-Soh Min; Kang-Young Lee; Seung-Kook Sohn; Chang-Hwan Cho
Journal:  Ann Surg       Date:  2009-06       Impact factor: 12.969

10.  MRI directed multidisciplinary team preoperative treatment strategy: the way to eliminate positive circumferential margins?

Authors:  S Burton; G Brown; I R Daniels; A R Norman; B Mason; D Cunningham
Journal:  Br J Cancer       Date:  2006-02-13       Impact factor: 7.640

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  3 in total

1.  Prognostic significance of lymph node ratio in patients undergoing abdominoperineal resection of rectum.

Authors:  M Tayyab; A Sharma; A W Macdonald; J Gunn; J E Hartley; J R T Monson
Journal:  Langenbecks Arch Surg       Date:  2012-08-09       Impact factor: 3.445

2.  Pilot study of a clinical pathway implementation in rectal cancer.

Authors:  Esther Uña; Francisco López-Lara
Journal:  Clin Med Insights Oncol       Date:  2010-10-12

3.  The Role of EGFR Inhibitors in the Treatment of Metastatic Anal Canal Carcinoma: A Case Series.

Authors:  Muhammad W Saif; Ewa Kontny; Kostas N Syrigos; Armin Shahrokni
Journal:  J Oncol       Date:  2011-06-13       Impact factor: 4.375

  3 in total

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