Literature DB >> 20455687

Intermittent preventive treatment against malaria: an update.

Roly D Gosling1, Matthew E Cairns, R Matthew Chico, Daniel Chandramohan.   

Abstract

Intermittent preventive treatment (IPT) against malaria is a malaria control strategy aimed at reducing the burden of malaria in certain high-risk groups, namely pregnant women and children. Three strategies - IPT in pregnancy (IPTp), infants (IPTi) and children (IPTc) - are reviewed here focusing on the mechanism of action, choice of drugs available, controversies and future research. Drugs for IPT need to be co-formulated, long acting, safe and preferably administered as a single dose. There is no obvious replacement for sulfadoxine-pyrimethamine, the most commonly utilized drug combination. All strategies face similar problems of rising drug resistance, falling malaria transmission and a policy shift from controlling disease to malaria elimination and eradication. IPT is an accepted form of malaria control, but to date only IPTp has been adopted as policy.

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Year:  2010        PMID： 20455687     DOI： 10.1586/eri.10.36

Source DB:  PubMed          Journal:  Expert Rev Anti Infect Ther        ISSN： 1478-7210            Impact factor:   5.091


  31 in total

1.  Pregnancy malaria: cryptic disease, apparent solution.

Authors:  Patrick Emmet Duffy; Michal Fried
Journal:  Mem Inst Oswaldo Cruz       Date:  2011-08       Impact factor: 2.743

2.  Intermittent Preventive Treatment with Dihydroartemisinin-Piperaquine in Ugandan Schoolchildren Selects for Plasmodium falciparum Transporter Polymorphisms That Modify Drug Sensitivity.

Authors:  Joaniter I Nankabirwa; Melissa D Conrad; Jennifer Legac; Stephen Tukwasibwe; Patrick Tumwebaze; Bonnie Wandera; Simon J Brooker; Sarah G Staedke; Moses R Kamya; Sam L Nsobya; Grant Dorsey; Philip J Rosenthal
Journal:  Antimicrob Agents Chemother       Date:  2016-09-23       Impact factor: 5.191

3.  Plasmodium falciparum and Plasmodium vivax genotypes and efficacy of intermittent preventive treatment in Papua New Guinea.

Authors:  Celine Barnadas; Nicolas Senn; Jonah Iga; Lincoln Timinao; Sarah Javati; Elisheba Malau; Patricia Rarau; John C Reeder; Peter Siba; Harin Karunajeewa; Peter A Zimmerman; Timothy M Davis; Ivo Mueller
Journal:  Antimicrob Agents Chemother       Date:  2014-08-25       Impact factor: 5.191

4.  Intermittent preventive therapy for malaria: arguments in favour of artesunate and sulphamethoxypyrazine - pyrimethamine combination.

Authors:  Frans Herwig Jansen
Journal:  Malar J       Date:  2011-03-29       Impact factor: 2.979

5.  Pharmacokinetics of piperaquine transfer into the breast milk of Melanesian mothers.

Authors:  Brioni R Moore; Sam Salman; John Benjamin; Madhu Page-Sharp; Gumal Yadi; Kevin T Batty; Peter M Siba; Ivo Mueller; Timothy M E Davis
Journal:  Antimicrob Agents Chemother       Date:  2015-05-11       Impact factor: 5.191

6.  Population pharmacokinetics, tolerability, and safety of dihydroartemisinin-piperaquine and sulfadoxine-pyrimethamine-piperaquine in pregnant and nonpregnant Papua New Guinean women.

Authors:  John M Benjamin; Brioni R Moore; Sam Salman; Madhu Page-Sharp; Somoyang Tawat; Gumal Yadi; Lina Lorry; Peter M Siba; Kevin T Batty; Leanne J Robinson; Ivo Mueller; Timothy M E Davis
Journal:  Antimicrob Agents Chemother       Date:  2015-05-11       Impact factor: 5.191

7.  Plasmodium falciparum msp1 and msp2 genetic diversity in parasites isolated from symptomatic and asymptomatic malaria subjects in the South of Benin.

Authors:  Hamirath Odée Lagnika; Azizath Moussiliou; Romuald Agonhossou; Pierre Sovegnon; Oswald Yédjinnavênan Djihinto; Adandé Assogba Medjigbodo; Laurette Djossou; Linda Eva Amoah; Aurore Ogouyemi-Hounto; Luc Salako Djogbenou
Journal:  Parasitol Res       Date:  2022-01-06       Impact factor: 2.289

8.  Efficacy, safety, and tolerability of three regimens for prevention of malaria: a randomized, placebo-controlled trial in Ugandan schoolchildren.

Authors:  Joaniter Nankabirwa; Bonnie Cundill; Sian Clarke; Narcis Kabatereine; Philip J Rosenthal; Grant Dorsey; Simon Brooker; Sarah G Staedke
Journal:  PLoS One       Date:  2010-10-19       Impact factor: 3.240

9.  Safety, tolerability and pharmacokinetic properties of coadministered azithromycin and piperaquine in pregnant Papua New Guinean women.

Authors:  Brioni R Moore; John M Benjamin; Siu On Auyeung; Sam Salman; Gumul Yadi; Suzanne Griffin; Madhu Page-Sharp; Kevin T Batty; Peter M Siba; Ivo Mueller; Stephen J Rogerson; Timothy Me Davis
Journal:  Br J Clin Pharmacol       Date:  2016-03-27       Impact factor: 4.335

10.  The Malaria in Pregnancy Library: a bibliometric review.

Authors:  Anna M van Eijk; Jenny Hill; Sue Povall; Alison Reynolds; Helen Wong; Feiko O Ter Kuile
Journal:  Malar J       Date:  2012-10-30       Impact factor: 2.979
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