| Literature DB >> 25155586 |
Celine Barnadas1, Nicolas Senn2, Jonah Iga3, Lincoln Timinao3, Sarah Javati3, Elisheba Malau4, Patricia Rarau3, John C Reeder5, Peter Siba3, Harin Karunajeewa6, Peter A Zimmerman7, Timothy M Davis8, Ivo Mueller9.
Abstract
Intermittent preventive treatment of infants (IPTi) reduces early childhood malaria-related morbidity. While genotypic drug resistance markers have proven useful in predicting the efficacy of antimalarial drugs in case management, there are few equivalent data relating to their protective efficacy when used as IPTi. The present data from an IPTi trial in Papua New Guinea demonstrate how these markers can predict protective efficacy of IPTi for both Plasmodium falciparum and Plasmodium vivax.Entities:
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Year: 2014 PMID: 25155586 PMCID: PMC4249390 DOI: 10.1128/AAC.03323-14
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191