| Literature DB >> 21443809 |
Abstract
Recent publications put a serious warning regarding the inefficacy of sulphadoxine-pyrimethamine (SP) for the intermittent preventive treatment of malaria in young children (IPTi). Recommendations for other therapies are being made. By using a different and better sulphonamide (sulphamethoxypyrazine), it is possible to manufacture fixed dose combination pills with artesunate and pyrimethamine. This combination permits a full therapy over 24 hours (dosing interval being 12 hours). It is recommended that this combination should be tested in future field studies of IPTi.Entities:
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Year: 2011 PMID: 21443809 PMCID: PMC3078902 DOI: 10.1186/1475-2875-10-70
Source DB: PubMed Journal: Malar J ISSN: 1475-2875 Impact factor: 2.979