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Literature DB >> 20441783

Recombinant elastin-mimetic biomaterials: Emerging applications in medicine.

Abstract

Biomaterials derived from protein-based block copolymers are increasingly investigated for potential application in medicine. In particular, recombinant elastin block copolymers provide significant opportunities to modulate material microstructure and can be processed in various forms, including particles, films, gels, and fiber networks. As a consequence, biological and mechanical responses of elastin-based biomaterials are tunable through precise control of block size and amino acid sequence. In this review, the synthesis of a set of elastin-mimetic triblock copolymers and their diverse processing methods for generating material platforms currently applied in medicine will be discussed.

Entities: CellLine Chemical Disease Gene Species

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Year: 2010 PMID： 20441783 PMCID： PMC2937194 DOI： 10.1016/j.addr.2010.04.007

Source DB: PubMed Journal: Adv Drug Deliv Rev ISSN： 0169-409X Impact factor: 15.470

66 in total

1. Elastomeric polypentapeptides cross-linked into matrixes and fibers.

Authors: J Lee; C W Macosko; D W Urry
Journal: Biomacromolecules Date: 2001 Impact factor: 6.988

Review 2. Biodegradable injectable in situ forming drug delivery systems.

Authors: A Hatefi; B Amsden
Journal: J Control Release Date: 2002-04-23 Impact factor: 9.776

3. Mechanism for the phase transition of a genetically engineered elastin model peptide (VPGIG)40 in aqueous solution.

Authors: Tetsuji Yamaoka; Takumi Tamura; Yuuki Seto; Tomoko Tada; Shigeru Kunugi; David A Tirrell
Journal: Biomacromolecules Date: 2003 Nov-Dec Impact factor: 6.988

Review 4. Biomaterials and scaffolds in reparative medicine.

Authors: Elliot L Chaikof; Howard Matthew; Joachim Kohn; Antonios G Mikos; Glenn D Prestwich; Christopher M Yip
Journal: Ann N Y Acad Sci Date: 2002-06 Impact factor: 5.691

Review 5. Injectable matrices and scaffolds for drug delivery in tissue engineering.

Authors: James D Kretlow; Leda Klouda; Antonios G Mikos
Journal: Adv Drug Deliv Rev Date: 2007-04-06 Impact factor: 15.470

6. Structured drug-eluting bioresorbable films: microstructure and release profile.

Authors: M Zilberman; Y Shifrovitch; M Aviv; M Hershkovitz
Journal: J Biomater Appl Date: 2008-07-16 Impact factor: 2.646

7. Albumin-coated vascular prostheses: A five-year follow-up.

Authors: H al-Khaffaf; D Charlesworth
Journal: J Vasc Surg Date: 1996-04 Impact factor: 4.268

8. Drug releasing behavior of hybrid micelles containing polypeptide triblock copolymer.

Authors: Jiaping Lin; Jianqi Zhu; Tao Chen; Shaoliang Lin; Chunhua Cai; Liangshun Zhang; Ying Zhuang; Xiao-Song Wang
Journal: Biomaterials Date: 2008-10-05 Impact factor: 12.479

9. An injectable and in situ-gelling biopolymer for sustained drug release following perineural administration.

Authors: Mohammed F Shamji; Lyman Whitlatch; Allan H Friedman; William J Richardson; Ashutosh Chilkoti; Lori A Setton
Journal: Spine (Phila Pa 1976) Date: 2008-04-01 Impact factor: 3.468

10. Recombinant human elastin polypeptides self-assemble into biomaterials with elastin-like properties.

Authors: Catherine M Bellingham; Margo A Lillie; John M Gosline; Glenda M Wright; Barry C Starcher; Allen J Bailey; Kimberly A Woodhouse; Fred W Keeley
Journal: Biopolymers Date: 2003-12 Impact factor: 2.505

19 in total

1. Toughening of Thermoresponsive Arrested Networks of Elastin-Like Polypeptides To Engineer Cytocompatible Tissue Scaffolds.

Authors: Matthew J Glassman; Reginald K Avery; Ali Khademhosseini; Bradley D Olsen
Journal: Biomacromolecules Date: 2016-01-20 Impact factor: 6.988

Recombinant elastin-mimetic biomaterials: Emerging applications in medicine.

1. Elastomeric polypentapeptides cross-linked into matrixes and fibers.

Review 2. Biodegradable injectable in situ forming drug delivery systems.

3. Mechanism for the phase transition of a genetically engineered elastin model peptide (VPGIG)40 in aqueous solution.

Review 4. Biomaterials and scaffolds in reparative medicine.

Review 5. Injectable matrices and scaffolds for drug delivery in tissue engineering.

6. Structured drug-eluting bioresorbable films: microstructure and release profile.

7. Albumin-coated vascular prostheses: A five-year follow-up.

8. Drug releasing behavior of hybrid micelles containing polypeptide triblock copolymer.

9. An injectable and in situ-gelling biopolymer for sustained drug release following perineural administration.

10. Recombinant human elastin polypeptides self-assemble into biomaterials with elastin-like properties.

1. Toughening of Thermoresponsive Arrested Networks of Elastin-Like Polypeptides To Engineer Cytocompatible Tissue Scaffolds.

Review 2. Protein-Engineered Functional Materials.

Review 3. Designing protein-based biomaterials for medical applications.

Review 4. Rational design of fiber forming supramolecular structures.

5. Natural and Genetically Engineered Proteins for Tissue Engineering.

Review 6. Insights into the role of elastin in vocal fold health and disease.

7. Multiple site-selective insertions of noncanonical amino acids into sequence-repetitive polypeptides.

8. Photoreactive elastin-like proteins for use as versatile bioactive materials and surface coatings.

9. Recombinant amphiphilic protein micelles for drug delivery.

Review 10. Engineering spatiotemporal organization and dynamics in synthetic cells.