| Literature DB >> 20439961 |
Diego Peres Alonso1, Dorcas Lamounier Costa, Ivete Lopes de Mendonça, Carlos Henrique Nery Costa, Paulo Eduardo Martins Ribolla.
Abstract
Leishmania infantum chagasi is the causative agent of visceral leishmaniasis in Brazil. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis of kinetoplast DNA (kDNA) minicircles was used to evaluate genetic profiles of 48 Leishmania infantum chagasi strains from dog and human parasite cultures, fresh collected dog bone marrow aspirates, and from infected sand flies. Results revealed that heterogeneity in kDNA minicircles depends mostly on the source of the samples, with cultured parasites showing a high degree of homogeneity.Entities:
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Year: 2010 PMID: 20439961 PMCID: PMC2861404 DOI: 10.4269/ajtmh.2010.09-0600
Source DB: PubMed Journal: Am J Trop Med Hyg ISSN: 0002-9637 Impact factor: 2.345