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Literature DB >> 20439426

The JARID2-PRC2 duality.

Abstract

Polycomb group proteins (PcG) are required for proper developmental regulation and cell fate commitment in metazoans. Recently, four studies reported the identification of JARID2, a JmjC domain-containing protein, as a component of the Polycomb-repressive complex 2 (PRC2), which is involved in implementing histone H3 Lys 27 methylation and transcriptional repression during development. Here, we discuss the implications of these studies for an improved understanding of PcG function in development.

Entities: Chemical Gene

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Year: 2010 PMID： 20439426 PMCID： PMC2861184 DOI： 10.1101/gad.1921610

Source DB: PubMed Journal: Genes Dev ISSN： 0890-9369 Impact factor: 11.361

50 in total

1. Jarid2 and PRC2, partners in regulating gene expression.

Authors: Gang Li; Raphael Margueron; Manching Ku; Pierre Chambon; Bradley E Bernstein; Danny Reinberg
Journal: Genes Dev Date: 2010-02-01 Impact factor: 11.361

2. Jumonji, a nuclear protein that is necessary for normal heart development.

Authors: Y Lee; A J Song; R Baker; B Micales; S J Conway; G E Lyons
Journal: Circ Res Date: 2000-05-12 Impact factor: 17.367

3. The polycomb-group gene Ezh2 is required for early mouse development.

Authors: D O'Carroll; S Erhardt; M Pagani; S C Barton; M A Surani; T Jenuwein
Journal: Mol Cell Biol Date: 2001-07 Impact factor: 4.272

4. Polycomblike PHD fingers mediate conserved interaction with enhancer of zeste protein.

Authors: S O'Connell; L Wang; S Robert; C A Jones; R Saint; R S Jones
Journal: J Biol Chem Date: 2001-09-24 Impact factor: 5.157

5. The polycomb group protein EZH2 is involved in progression of prostate cancer.

Authors: Sooryanarayana Varambally; Saravana M Dhanasekaran; Ming Zhou; Terrence R Barrette; Chandan Kumar-Sinha; Martin G Sanda; Debashis Ghosh; Kenneth J Pienta; Richard G A B Sewalt; Arie P Otte; Mark A Rubin; Arul M Chinnaiyan
Journal: Nature Date: 2002-10-10 Impact factor: 49.962

6. Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells.

Authors: Jamy C Peng; Anton Valouev; Tomek Swigut; Junmei Zhang; Yingming Zhao; Arend Sidow; Joanna Wysocka
Journal: Cell Date: 2009-12-24 Impact factor: 41.582

7. A jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9.

Authors: Haruki Shirato; Satoko Ogawa; Kuniko Nakajima; Masayo Inagawa; Mizuyo Kojima; Makoto Tachibana; Yoichi Shinkai; Takashi Takeuchi
Journal: J Biol Chem Date: 2008-11-14 Impact factor: 5.157

8. Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling.

Authors: Anne-Marie Martinez; Bernd Schuettengruber; Samy Sakr; Ana Janic; Cayetano Gonzalez; Giacomo Cavalli
Journal: Nat Genet Date: 2009-09-13 Impact factor: 38.330

9. A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling.

Authors: Anne-Kathrin Classen; Brandon D Bunker; Kieran F Harvey; Thomas Vaccari; David Bilder
Journal: Nat Genet Date: 2009-09-13 Impact factor: 38.330

10. Role of the polycomb protein EED in the propagation of repressive histone marks.

Authors: Raphael Margueron; Neil Justin; Katsuhito Ohno; Miriam L Sharpe; Jinsook Son; William J Drury; Philipp Voigt; Stephen R Martin; William R Taylor; Valeria De Marco; Vincenzo Pirrotta; Danny Reinberg; Steven J Gamblin
Journal: Nature Date: 2009-09-20 Impact factor: 49.962

37 in total

Review 1. The dynamic interplay in chromatin remodeling factors polycomb and trithorax proteins in response to DNA damage.

Authors: Shuang Liu; Yongguang Tao; Xiang Chen; Ya Cao
Journal: Mol Biol Rep Date: 2011-12-28 Impact factor: 2.316

Review 2. Mechanisms regulating epidermal stem cells.

Authors: Benjamin Beck; Cédric Blanpain
Journal: EMBO J Date: 2012-03-20 Impact factor: 11.598

Review 3. PCL2 modulates gene regulatory networks controlling self-renewal and commitment in embryonic stem cells.

Authors: Emily Walker; Janet L Manias; Wing Y Chang; William L Stanford
Journal: Cell Cycle Date: 2011-01-01 Impact factor: 4.534

Review 4. Balancing histone methylation activities in psychiatric disorders.

Authors: Cyril Jayakumar Peter; Schahram Akbarian
Journal: Trends Mol Med Date: 2011-03-21 Impact factor: 11.951

Review 5. SET for life: biochemical activities and biological functions of SET domain-containing proteins.

Authors: Hans-Martin Herz; Alexander Garruss; Ali Shilatifard
Journal: Trends Biochem Sci Date: 2013-10-20 Impact factor: 13.807

6. Chromatin-modifying agents for epigenetic reprogramming and endogenous neural stem cell-mediated repair in stroke.

Authors: Irfan A Qureshi; Mark F Mehler
Journal: Transl Stroke Res Date: 2011-03-01 Impact factor: 6.829

7. Jarid2 regulates mouse epidermal stem cell activation and differentiation.

Authors: Stefania Mejetta; Lluis Morey; Gloria Pascual; Bernd Kuebler; Matthew R Mysliwiec; Youngsook Lee; Ramin Shiekhattar; Luciano Di Croce; Salvador Aznar Benitah
Journal: EMBO J Date: 2011-08-02 Impact factor: 11.598

Review 8. CpG islands and the regulation of transcription.

Authors: Aimée M Deaton; Adrian Bird
Journal: Genes Dev Date: 2011-05-15 Impact factor: 11.361

9. The histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival.

Authors: Ranjula Wijayatunge; Liang-Fu Chen; Young May Cha; Anthony S Zannas; Christopher L Frank; Anne E West
Journal: Mol Cell Neurosci Date: 2014-06-28 Impact factor: 4.314

10. A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1.

Authors: Masamitsu Negishi; Atsunori Saraya; Shinobu Mochizuki; Kristian Helin; Haruhiko Koseki; Atsushi Iwama
Journal: PLoS One Date: 2010-08-24 Impact factor: 3.240