Literature DB >> 21429800

Balancing histone methylation activities in psychiatric disorders.

Cyril Jayakumar Peter1, Schahram Akbarian.   

Abstract

Alterations in histone lysine methylation and other epigenetic regulators of gene expression contribute to changes in brain transcriptomes in mood and psychosis spectrum disorders, including depression and schizophrenia. Genetic association studies and animal models implicate multiple lysine methyltransferases and demethylases in the neurobiology of emotion and cognition. Here, we review the role of histone lysine methylation and transcriptional regulation in normal and diseased neurodevelopment and discuss various methyltransferases and demethylases as potential therapeutic targets in the treatment of neuropsychiatric disease.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 21429800      PMCID： PMC3134618          DOI： 10.1016/j.molmed.2011.02.003

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN： 1471-4914            Impact factor:   11.951


  92 in total

1.  Genome-wide atlas of gene expression in the adult mouse brain.

Authors:  Ed S Lein; Michael J Hawrylycz; Nancy Ao; Mikael Ayres; Amy Bensinger; Amy Bernard; Andrew F Boe; Mark S Boguski; Kevin S Brockway; Emi J Byrnes; Lin Chen; Li Chen; Tsuey-Ming Chen; Mei Chi Chin; Jimmy Chong; Brian E Crook; Aneta Czaplinska; Chinh N Dang; Suvro Datta; Nick R Dee; Aimee L Desaki; Tsega Desta; Ellen Diep; Tim A Dolbeare; Matthew J Donelan; Hong-Wei Dong; Jennifer G Dougherty; Ben J Duncan; Amanda J Ebbert; Gregor Eichele; Lili K Estin; Casey Faber; Benjamin A Facer; Rick Fields; Shanna R Fischer; Tim P Fliss; Cliff Frensley; Sabrina N Gates; Katie J Glattfelder; Kevin R Halverson; Matthew R Hart; John G Hohmann; Maureen P Howell; Darren P Jeung; Rebecca A Johnson; Patrick T Karr; Reena Kawal; Jolene M Kidney; Rachel H Knapik; Chihchau L Kuan; James H Lake; Annabel R Laramee; Kirk D Larsen; Christopher Lau; Tracy A Lemon; Agnes J Liang; Ying Liu; Lon T Luong; Jesse Michaels; Judith J Morgan; Rebecca J Morgan; Marty T Mortrud; Nerick F Mosqueda; Lydia L Ng; Randy Ng; Geralyn J Orta; Caroline C Overly; Tu H Pak; Sheana E Parry; Sayan D Pathak; Owen C Pearson; Ralph B Puchalski; Zackery L Riley; Hannah R Rockett; Stephen A Rowland; Joshua J Royall; Marcos J Ruiz; Nadia R Sarno; Katherine Schaffnit; Nadiya V Shapovalova; Taz Sivisay; Clifford R Slaughterbeck; Simon C Smith; Kimberly A Smith; Bryan I Smith; Andy J Sodt; Nick N Stewart; Kenda-Ruth Stumpf; Susan M Sunkin; Madhavi Sutram; Angelene Tam; Carey D Teemer; Christina Thaller; Carol L Thompson; Lee R Varnam; Axel Visel; Ray M Whitlock; Paul E Wohnoutka; Crissa K Wolkey; Victoria Y Wong; Matthew Wood; Murat B Yaylaoglu; Rob C Young; Brian L Youngstrom; Xu Feng Yuan; Bin Zhang; Theresa A Zwingman; Allan R Jones
Journal:  Nature       Date:  2006-12-06       Impact factor: 49.962

2.  Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini.

Authors:  Sean D Taverna; Beatrix M Ueberheide; Yifan Liu; Alan J Tackett; Robert L Diaz; Jeffrey Shabanowitz; Brian T Chait; Donald F Hunt; C David Allis
Journal:  Proc Natl Acad Sci U S A       Date:  2007-02-06       Impact factor: 11.205

3.  The presynaptic component of the serotonergic system is required for clozapine's efficacy.

Authors:  Prem N Yadav; Atheir I Abbas; Martilias S Farrell; Vincent Setola; Noah Sciaky; Xi-Ping Huang; Wesley K Kroeze; LaTasha K Crawford; David A Piel; Michael J Keiser; John J Irwin; Brian K Shoichet; Evan S Deneris; Jay Gingrich; Sheryl G Beck; Bryan L Roth
Journal:  Neuropsychopharmacology       Date:  2010-11-03       Impact factor: 7.853

4.  Histone modification levels are predictive for gene expression.

Authors:  Rosa Karlić; Ho-Ryun Chung; Julia Lasserre; Kristian Vlahovicek; Martin Vingron
Journal:  Proc Natl Acad Sci U S A       Date:  2010-02-01       Impact factor: 11.205

5.  Histone methylation regulates memory formation.

Authors:  Swati Gupta; Se Y Kim; Sonja Artis; David L Molfese; Armin Schumacher; J David Sweatt; Richard E Paylor; Farah D Lubin
Journal:  J Neurosci       Date:  2010-03-10       Impact factor: 6.167

6.  Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex.

Authors:  João D Pereira; Stephen N Sansom; James Smith; Marc-Werner Dobenecker; Alexander Tarakhovsky; Frederick J Livesey
Journal:  Proc Natl Acad Sci U S A       Date:  2010-08-23       Impact factor: 11.205

7.  Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma.

Authors:  María Berdasco; Santiago Ropero; Fernando Setien; Mario F Fraga; Pablo Lapunzina; Régine Losson; Miguel Alaminos; Nai-Kong Cheung; Nazneen Rahman; Manel Esteller
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-14       Impact factor: 11.205

8.  Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells.

Authors:  Jamy C Peng; Anton Valouev; Tomek Swigut; Junmei Zhang; Yingming Zhao; Arend Sidow; Joanna Wysocka
Journal:  Cell       Date:  2009-12-24       Impact factor: 41.582

Review 9.  The genetics and biology of DISC1--an emerging role in psychosis and cognition.

Authors:  David J Porteous; Pippa Thomson; Nicholas J Brandon; J Kirsty Millar
Journal:  Biol Psychiatry       Date:  2006-07-15       Impact factor: 13.382

10.  The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment.

Authors:  Thomas Burgold; Fabio Spreafico; Francesca De Santa; Maria Grazia Totaro; Elena Prosperini; Gioacchino Natoli; Giuseppe Testa
Journal:  PLoS One       Date:  2008-08-21       Impact factor: 3.240
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  43 in total

Review 1.  Epigenetics components of aging in the central nervous system.

Authors:  Yue-Qiang Zhao; I King Jordan; Victoria V Lunyak
Journal:  Neurotherapeutics       Date:  2013-10       Impact factor: 7.620

2.  Targeting epigenetics and non-coding RNAs in atherosclerosis: from mechanisms to therapeutics.

Authors:  Suowen Xu; Danielle Kamato; Peter J Little; Shinichi Nakagawa; Jaroslav Pelisek; Zheng Gen Jin
Journal:  Pharmacol Ther       Date:  2018-11-13       Impact factor: 12.310

Review 3.  Histone regulation in the CNS: basic principles of epigenetic plasticity.

Authors:  Ian Maze; Kyung-Min Noh; C David Allis
Journal:  Neuropsychopharmacology       Date:  2012-07-25       Impact factor: 7.853

Review 4.  Kraepelin revisited: schizophrenia from degeneration to failed regeneration.

Authors:  P Falkai; M J Rossner; T G Schulze; A Hasan; M M Brzózka; B Malchow; W G Honer; A Schmitt
Journal:  Mol Psychiatry       Date:  2015-03-31       Impact factor: 15.992

Review 5.  Neurobiological effects of aerobic exercise, with a focus on patients with schizophrenia.

Authors:  Isabel Maurus; Alkomiet Hasan; Astrid Röh; Shun Takahashi; Boris Rauchmann; Daniel Keeser; Berend Malchow; Andrea Schmitt; Peter Falkai
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2019-05-21       Impact factor: 5.270

6.  Early-Life Social Isolation-Induced Depressive-Like Behavior in Rats Results in Microglial Activation and Neuronal Histone Methylation that Are Mitigated by Minocycline.

Authors:  Hong-Tao Wang; Fu-Lian Huang; Zhao-Lan Hu; Wen-Juan Zhang; Xiao-Qing Qiao; Yan-Qing Huang; Ru-Ping Dai; Fang Li; Chang-Qi Li
Journal:  Neurotox Res       Date:  2017-01-16       Impact factor: 3.911

Review 7.  Toward development of epigenetic drugs for central nervous system disorders: Modulating neuroplasticity via H3K4 methylation.

Authors:  Emily L Ricq; Jacob M Hooker; Stephen J Haggarty
Journal:  Psychiatry Clin Neurosci       Date:  2016-09-07       Impact factor: 5.188

8.  Prefrontal cortex expression of chromatin modifier genes in male WSP and WSR mice changes across ethanol dependence, withdrawal, and abstinence.

Authors:  Joel G Hashimoto; David P Gavin; Kristine M Wiren; John C Crabbe; Marina Guizzetti
Journal:  Alcohol       Date:  2017-03-14       Impact factor: 2.405

9.  Alterations in the neuropeptide galanin system in major depressive disorder involve levels of transcripts, methylation, and peptide.

Authors:  Swapnali Barde; Joelle Rüegg; Josée Prud'homme; Tomas J Ekström; Miklos Palkovits; Gustavo Turecki; Gyorgy Bagdy; Robert Ihnatko; Elvar Theodorsson; Gabriella Juhasz; Rochellys Diaz-Heijtz; Naguib Mechawar; Tomas G M Hökfelt
Journal:  Proc Natl Acad Sci U S A       Date:  2016-12-09       Impact factor: 11.205

10.  Epigenetics: Stress makes its molecular mark.

Authors:  Eric J Nestler
Journal:  Nature       Date:  2012-10-11       Impact factor: 49.962
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