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Literature DB >> 20436975

A bioorthogonal chemistry strategy for probing protein lipidation in live cells.

Wenjiao Song¹, Zhipeng Yu, Michael M Madden, Qing Lin.

Abstract

We report a chemical lipidation model for the study of protein lipidations in vitro and in live mammalian cells based on a bioorthogonal, photoinduced tetrazole-alkene cycloaddition reaction.

Entities: CellLine Chemical Disease Gene Species

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Year: 2010 PMID： 20436975 PMCID： PMC2922461 DOI： 10.1039/c003470c

Source DB: PubMed Journal: Mol Biosyst ISSN： 1742-2051

25 in total

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Review 3. Mechanisms of Ras protein targeting in mammalian cells.

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Review 4. Ras proteins: different signals from different locations.

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Review 5. Bioorthogonal chemistry: recent progress and future directions.

Authors: Reyna K V Lim; Qing Lin
Journal: Chem Commun (Camb) Date: 2010-01-21 Impact factor: 6.222

6. A photoinducible 1,3-dipolar cycloaddition reaction for rapid, selective modification of tetrazole-containing proteins.

Authors: Wenjiao Song; Yizhong Wang; Jun Qu; Michael M Madden; Qing Lin
Journal: Angew Chem Int Ed Engl Date: 2008 Impact factor: 15.336

7. Selective functionalization of a genetically encoded alkene-containing protein via "photoclick chemistry" in bacterial cells.

Authors: Wenjiao Song; Yizhong Wang; Jun Qu; Qing Lin
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Review 9. The guanine nucleotide-binding switch in three dimensions.

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10. Fast alkene functionalization in vivo by Photoclick chemistry: HOMO lifting of nitrile imine dipoles.

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8 in total

Review 1. Photo-Triggered Click Chemistry for Biological Applications.

Authors: András Herner; Qing Lin
Journal: Top Curr Chem (Cham) Date: 2015-12-11

2. Synthesis of macrocyclic tetrazoles for rapid photoinduced bioorthogonal 1,3-dipolar cycloaddition reactions.

Authors: Zhipeng Yu; Reyna K V Lim; Qing Lin
Journal: Chemistry Date: 2010-12-03 Impact factor: 5.236

3. Rapid, photoactivatable turn-on fluorescent probes based on an intramolecular photoclick reaction.

Authors: Zhipeng Yu; Lok Yin Ho; Qing Lin
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4. A biosynthetic route to photoclick chemistry on proteins.

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Review 5. Photoinducible bioorthogonal chemistry: a spatiotemporally controllable tool to visualize and perturb proteins in live cells.

Authors: Reyna K V Lim; Qing Lin
Journal: Acc Chem Res Date: 2011-05-20 Impact factor: 22.384