Literature DB >> 20430952

Lessons from photoreceptors: turning off g-protein signaling in living cells.

Marie E Burns1, Edward N Pugh.   

Abstract

Phototransduction in retinal rods is one of the most extensively studied G-protein signaling systems. In recent years, our understanding of the biochemical steps that regulate the deactivation of the rod's response to light has greatly improved. Here, we summarize recent advances and highlight some of the remaining puzzles in this model signaling system.

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Year:  2010        PMID： 20430952      PMCID： PMC2880230          DOI： 10.1152/physiol.00001.2010

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  127 in total

1.  RGS9 concentration matters in rod phototransduction.

Authors:  Marie E Burns; Edward N Pugh
Journal:  Biophys J       Date:  2009-09-16       Impact factor: 4.033

2.  Molecular origin of continuous dark noise in rod photoreceptors.

Authors:  F Rieke; D A Baylor
Journal:  Biophys J       Date:  1996-11       Impact factor: 4.033

3.  Kinetics of desensitization induced by saturating flashes in toad and salamander rods.

Authors:  J G Murnick; T D Lamb
Journal:  J Physiol       Date:  1996-08-15       Impact factor: 5.182

Review 4.  Amplification and kinetics of the activation steps in phototransduction.

Authors:  E N Pugh; T D Lamb
Journal:  Biochim Biophys Acta       Date:  1993-03-01

5.  Defects in the rhodopsin kinase gene in the Oguchi form of stationary night blindness.

Authors:  S Yamamoto; K C Sippel; E L Berson; T P Dryja
Journal:  Nat Genet       Date:  1997-02       Impact factor: 38.330

6.  A novel mutation in GRK1 causes Oguchi disease in a consanguineous Pakistani family.

Authors:  Maleeha Azam; Rob W J Collin; Muhammad Imran Khan; Syed Tahir Abbas Shah; Nadeem Qureshi; Muhammad Ajmal; Anneke I den Hollander; Raheel Qamar; Frans P M Cremers
Journal:  Mol Vis       Date:  2009-09-05       Impact factor: 2.367

7.  Mechanistic studies on rhodopsin kinase. Light-dependent phosphorylation of C-terminal peptides of rhodopsin.

Authors:  N G Brown; C Fowles; R Sharma; M Akhtar
Journal:  Eur J Biochem       Date:  1992-09-15

8.  Light-dependent delay in the falling phase of the retinal rod photoresponse.

Authors:  D R Pepperberg; M C Cornwall; M Kahlert; K P Hofmann; J Jin; G J Jones; H Ripps
Journal:  Vis Neurosci       Date:  1992-01       Impact factor: 3.241

9.  Enhanced arrestin facilitates recovery and protects rods lacking rhodopsin phosphorylation.

Authors:  Xiufeng Song; Sergey A Vishnivetskiy; Owen P Gross; Katrina Emelianoff; Ana Mendez; Jeannie Chen; Eugenia V Gurevich; Marie E Burns; Vsevolod V Gurevich
Journal:  Curr Biol       Date:  2009-04-09       Impact factor: 10.834

10.  The kinetics of inactivation of the rod phototransduction cascade with constant Ca2+i.

Authors:  A Lyubarsky; S Nikonov; E N Pugh
Journal:  J Gen Physiol       Date:  1996-01       Impact factor: 4.086
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  50 in total

Review 1.  Rod and cone visual pigments and phototransduction through pharmacological, genetic, and physiological approaches.

Authors:  Vladimir J Kefalov
Journal:  J Biol Chem       Date:  2011-11-10       Impact factor: 5.157

2.  Characterization of conformational changes and protein-protein interactions of rod photoreceptor phosphodiesterase (PDE6).

Authors:  Suzanne L Matte; Thomas M Laue; Rick H Cote
Journal:  J Biol Chem       Date:  2012-04-18       Impact factor: 5.157

Review 3.  Speed, sensitivity, and stability of the light response in rod and cone photoreceptors: facts and models.

Authors:  Juan I Korenbrot
Journal:  Prog Retin Eye Res       Date:  2012-05-29       Impact factor: 21.198

Review 4.  Microbial and animal rhodopsins: structures, functions, and molecular mechanisms.

Authors:  Oliver P Ernst; David T Lodowski; Marcus Elstner; Peter Hegemann; Leonid S Brown; Hideki Kandori
Journal:  Chem Rev       Date:  2013-12-23       Impact factor: 60.622

5.  Molecular evolutionary analysis of vertebrate transducins: a role for amino acid variation in photoreceptor deactivation.

Authors:  Yi G Lin; Cameron J Weadick; Francesco Santini; Belinda S W Chang
Journal:  J Mol Evol       Date:  2013-10-22       Impact factor: 2.395

Review 6.  Timing is everything: GTPase regulation in phototransduction.

Authors:  Vadim Y Arshavsky; Theodore G Wensel
Journal:  Invest Ophthalmol Vis Sci       Date:  2013-11-21       Impact factor: 4.799

7.  In vivo observation of transient photoreceptor movement correlated with oblique light stimulation.

Authors:  Yiming Lu; Changgeng Liu; Xincheng Yao
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2018-02-20

8.  G protein signaling in the retina and beyond: the Cogan lecture.

Authors:  Kirill A Martemyanov
Journal:  Invest Ophthalmol Vis Sci       Date:  2014-12-15       Impact factor: 4.799

9.  Determining consequences of retinal membrane guanylyl cyclase (RetGC1) deficiency in human Leber congenital amaurosis en route to therapy: residual cone-photoreceptor vision correlates with biochemical properties of the mutants.

Authors:  Samuel G Jacobson; Artur V Cideciyan; Igor V Peshenko; Alexander Sumaroka; Elena V Olshevskaya; Lihui Cao; Sharon B Schwartz; Alejandro J Roman; Melani B Olivares; Sam Sadigh; King-Wai Yau; Elise Heon; Edwin M Stone; Alexander M Dizhoor
Journal:  Hum Mol Genet       Date:  2012-10-03       Impact factor: 6.150

10.  Rapid light-induced activation of retinal microglia in mice lacking Arrestin-1.

Authors:  Emily S Levine; Azhar Zam; Pengfei Zhang; Alina Pechko; Xinlei Wang; Paul FitzGerald; Edward N Pugh; Robert J Zawadzki; Marie E Burns
Journal:  Vision Res       Date:  2014-08-01       Impact factor: 1.886
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