Literature DB >> 29950751

In vivo observation of transient photoreceptor movement correlated with oblique light stimulation.

Yiming Lu1, Changgeng Liu1, Xincheng Yao1,2.   

Abstract

Rod-dominated transient retinal phototropism (TRP) has been observed in freshly isolated retinas, promising a noninvasive biomarker for high resolution assessment of retinal physiology. However, in vivo mapping of TRP is challenging due to its fast time course and sub-cellular signal magnitude. By developing a line-scanning and virtually structured detection based super-resolution ophthalmoscope, we report here in vivo observation of TRP in frog retina. In vivo characterization of TRP time course and magnitude were implemented by using variable light stimulus intensities.

Entities:  

Keywords:  Retina; functional imaging; ophthalmology; photoreceptor; super-resolution microscopy

Year:  2018        PMID： 29950751      PMCID： PMC6016829          DOI： 10.1117/12.2287262

Source DB:  PubMed          Journal:  Proc SPIE Int Soc Opt Eng        ISSN： 0277-786X


  30 in total

1.  Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: a morphological and ERG study.

Authors:  Claudia Gargini; Eva Terzibasi; Francesca Mazzoni; Enrica Strettoi
Journal:  J Comp Neurol       Date:  2007-01-10       Impact factor: 3.215

2.  Dynamic near-infrared imaging reveals transient phototropic change in retinal rod photoreceptors.

Authors:  Rongwen Lu; Alexander M Levy; Qiuxiang Zhang; Steven J Pittler; Xincheng Yao
Journal:  J Biomed Opt       Date:  2013-10       Impact factor: 3.170

Review 3.  Age-related macular degeneration.

Authors:  Rama D Jager; William F Mieler; Joan W Miller
Journal:  N Engl J Med       Date:  2008-06-12       Impact factor: 91.245

Review 4.  Photoreceptor membrane proteins, phototransduction, and retinal degenerative diseases. The Friedenwald Lecture.

Authors:  R S Molday
Journal:  Invest Ophthalmol Vis Sci       Date:  1998-12       Impact factor: 4.799

5.  Deactivation of photoactivated rhodopsin by rhodopsin-kinase and arrestin.

Authors:  H Kühn; U Wilden
Journal:  J Recept Res       Date:  1987

6.  Stimulus-evoked outer segment changes occur before the hyperpolarization of retinal photoreceptors.

Authors:  Yiming Lu; Benquan Wang; David R Pepperberg; Xincheng Yao
Journal:  Biomed Opt Express       Date:  2016-12-02       Impact factor: 3.732

Review 7.  Amplification and kinetics of the activation steps in phototransduction.

Authors:  E N Pugh; T D Lamb
Journal:  Biochim Biophys Acta       Date:  1993-03-01

8.  Comparison of Visual Function in Older Eyes in the Earliest Stages of Age-related Macular Degeneration to Those in Normal Macular Health.

Authors:  Cynthia Owsley; Carrie Huisingh; Mark E Clark; Gregory R Jackson; Gerald McGwin
Journal:  Curr Eye Res       Date:  2015-03-24       Impact factor: 2.424

9.  Functional optical coherence tomography reveals transient phototropic change of photoreceptor outer segments.

Authors:  Benquan Wang; Qiuxiang Zhang; Rongwen Lu; Yanan Zhi; Xincheng Yao
Journal:  Opt Lett       Date:  2014-12-15       Impact factor: 3.776

10.  Comparative investigation of stimulus-evoked rod outer segment movement and retinal electrophysiological activity.

Authors:  Yiming Lu; Benquan Wang; Xincheng Yao
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2017-02-16
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.