Literature DB >> 2041100

The sequence of human immunodeficiency virus type 2 circle junction suggests that integration protein cleaves the ends of linear DNA asymmetrically.

J M Whitcomb1, S H Hughes.   

Abstract

The sequence of the human immunodeficiency virus type 2 circle junction was determined. The most common sequence found between the conserved CA and TG dinucleotides at the ends of the integrated provirus was five bases long (GGTAC). This suggests that the integration of human immunodeficiency virus type 2 DNA is accompanied by the asymmetric loss of two and three bases, respectively, from the U3 and U5 ends of the linear double-stranded DNA prior to integration.

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Year:  1991        PMID： 2041100      PMCID： PMC241426     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  32 in total

1.  Complete nucleotide sequence of the AIDS virus, HTLV-III.

Authors:  L Ratner; W Haseltine; R Patarca; K J Livak; B Starcich; S F Josephs; E R Doran; J A Rafalski; E A Whitehorn; K Baumeister
Journal:  Nature       Date:  1985 Jan 24-30       Impact factor: 49.962

2.  Nucleotide sequence and expression of an AIDS-associated retrovirus (ARV-2).

Authors:  R Sanchez-Pescador; M D Power; P J Barr; K S Steimer; M M Stempien; S L Brown-Shimer; W W Gee; A Renard; A Randolph; J A Levy
Journal:  Science       Date:  1985-02-01       Impact factor: 47.728

3.  Correct integration of retroviral DNA in vitro.

Authors:  P O Brown; B Bowerman; H E Varmus; J M Bishop
Journal:  Cell       Date:  1987-05-08       Impact factor: 41.582

4.  Sequence and spacing requirements of a retrovirus integration site.

Authors:  J Colicelli; S P Goff
Journal:  J Mol Biol       Date:  1988-01-05       Impact factor: 5.469

5.  Nucleotide sequence of the AIDS virus, LAV.

Authors:  S Wain-Hobson; P Sonigo; O Danos; S Cole; M Alizon
Journal:  Cell       Date:  1985-01       Impact factor: 41.582

6.  Selective extraction of polyoma DNA from infected mouse cell cultures.

Authors:  B Hirt
Journal:  J Mol Biol       Date:  1967-06-14       Impact factor: 5.469

7.  The terminal nucleotides of retrovirus DNA are required for integration but not virus production.

Authors:  A T Panganiban; H M Temin
Journal:  Nature       Date:  1983 Nov 10-16       Impact factor: 49.962

8.  Genome organization and transactivation of the human immunodeficiency virus type 2.

Authors:  M Guyader; M Emerman; P Sonigo; F Clavel; L Montagnier; M Alizon
Journal:  Nature       Date:  1987 Apr 16-22       Impact factor: 49.962

9.  Terminal nucleotides of the preintegrative linear form of HIV-1 DNA deduced from the sequence of circular DNA junctions.

Authors:  J Kulkosky; R A Katz; A M Skalka
Journal:  J Acquir Immune Defic Syndr (1988)       Date:  1990

10.  Mutants and pseudorevertants of Moloney murine leukemia virus with alterations at the integration site.

Authors:  J Colicelli; S P Goff
Journal:  Cell       Date:  1985-09       Impact factor: 41.582
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  11 in total

Review 1.  Multifaceted HIV integrase functionalities and therapeutic strategies for their inhibition.

Authors:  Alan N Engelman
Journal:  J Biol Chem       Date:  2019-08-29       Impact factor: 5.157

2.  Human immunodeficiency virus type 2 preintegration complexes: activities in vitro and response to inhibitors.

Authors:  M S Hansen; F D Bushman
Journal:  J Virol       Date:  1997-04       Impact factor: 5.103

3.  Retrovirus-like end processing of the tobacco Tnt1 retrotransposon linear intermediates of replication.

Authors:  F Feuerbach; J Drouaud; H Lucas
Journal:  J Virol       Date:  1997-05       Impact factor: 5.103

4.  Mutations in the U5 sequences adjacent to the primer binding site do not affect tRNA cleavage by rous sarcoma virus RNase H but do cause aberrant integrations in vivo.

Authors:  Jangsuk Oh; Kevin W Chang; Stephen H Hughes
Journal:  J Virol       Date:  2006-01       Impact factor: 5.103

5.  Retroviral integrase: Structure, mechanism, and inhibition.

Authors:  Dario Oliveira Passos; Min Li; Robert Craigie; Dmitry Lyumkis
Journal:  Enzymes       Date:  2021-08-23

6.  Mutations in the U5 region adjacent to the primer binding site affect tRNA cleavage by human immunodeficiency virus type 1 reverse transcriptase in vivo.

Authors:  Jangsuk Oh; Mary Jane McWilliams; John G Julias; Stephen H Hughes
Journal:  J Virol       Date:  2007-11-07       Impact factor: 5.103

7.  Both substrate and target oligonucleotide sequences affect in vitro integration mediated by human immunodeficiency virus type 1 integrase protein produced in Saccharomyces cerevisiae.

Authors:  A D Leavitt; R B Rose; H E Varmus
Journal:  J Virol       Date:  1992-04       Impact factor: 5.103

8.  Mutational analysis of the integrase protein of human immunodeficiency virus type 2.

Authors:  D C van Gent; A A Groeneger; R H Plasterk
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-15       Impact factor: 11.205

9.  A novel function for spumaretrovirus integrase: an early requirement for integrase-mediated cleavage of 2 LTR circles.

Authors:  Olivier Delelis; Caroline Petit; Herve Leh; Gladys Mbemba; Jean-François Mouscadet; Pierre Sonigo
Journal:  Retrovirology       Date:  2005-05-18       Impact factor: 4.602

10.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1991-11-11       Impact factor: 16.971
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