| Literature DB >> 3031510 |
M Guyader, M Emerman, P Sonigo, F Clavel, L Montagnier, M Alizon.
Abstract
Analysis of the nucleotide sequence of the human retrovirus associated with AIDS in West Africa, HIV-2, shows that it is evolutionarily distant from the previously characterized HIV-1. We suggest that these viruses existed long before the current AIDS epidemics. Their biological properties are conserved in spite of limited sequence homology; this may help the determination of the structure-function relationships of the different viral elements.Entities:
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Year: 1987 PMID: 3031510 DOI: 10.1038/326662a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962