Literature DB >> 6316141

The terminal nucleotides of retrovirus DNA are required for integration but not virus production.

A T Panganiban, H M Temin.   

Abstract

Deletion of specific nucleotides at either end of the long terminal repeat of the avian retrovirus, spleen necrosis virus, results in replication-competent but integration-defective virus. This result supports two conclusions: (1) the 5-base pair terminal inverted repeats and three to seven adjacent nucleotides are required for integration; (2) integration of retrovirus DNA is not required for retrovirus gene expression.

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Year:  1983        PMID： 6316141     DOI： 10.1038/306155a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  85 in total

1.  Substrate sequence selection by retroviral integrase.

Authors:  H Zhou; G J Rainey; S K Wong; J M Coffin
Journal:  J Virol       Date:  2001-02       Impact factor: 5.103

2.  Identification of sequences downstream of the primer binding site that are important for efficient replication of human immunodeficiency virus type 1.

Authors:  X Li; C Liang; Y Quan; R Chandok; M Laughrea; M A Parniak; L Kleiman; M A Wainberg
Journal:  J Virol       Date:  1997-08       Impact factor: 5.103

3.  Removal of 3'-OH-terminal nucleotides from blunt-ended long terminal repeat termini by the avian retrovirus integration protein.

Authors:  A C Vora; M L Fitzgerald; D P Grandgenett
Journal:  J Virol       Date:  1990-11       Impact factor: 5.103

Review 4.  HIV DNA integration.

Authors:  Robert Craigie; Frederic D Bushman
Journal:  Cold Spring Harb Perspect Med       Date:  2012-07       Impact factor: 6.915

5.  The sequence of human immunodeficiency virus type 2 circle junction suggests that integration protein cleaves the ends of linear DNA asymmetrically.

Authors:  J M Whitcomb; S H Hughes
Journal:  J Virol       Date:  1991-07       Impact factor: 5.103

6.  A mutation in integrase can compensate for mutations in the simian immunodeficiency virus att site.

Authors:  Z Du; P O Ilyinskii; K Lally; R C Desrosiers; A Engelman
Journal:  J Virol       Date:  1997-11       Impact factor: 5.103

7.  A mutation at one end of Moloney murine leukemia virus DNA blocks cleavage of both ends by the viral integrase in vivo.

Authors:  J E Murphy; S P Goff
Journal:  J Virol       Date:  1992-08       Impact factor: 5.103

8.  Early transcription from nonintegrated DNA in human immunodeficiency virus infection.

Authors:  Yuntao Wu; Jon W Marsh
Journal:  J Virol       Date:  2003-10       Impact factor: 5.103

9.  An integration-defective U5 deletion mutant of human immunodeficiency virus type 1 reverts by eliminating additional long terminal repeat sequences.

Authors:  E Vicenzi; D S Dimitrov; A Engelman; T S Migone; D F Purcell; J Leonard; G Englund; M A Martin
Journal:  J Virol       Date:  1994-12       Impact factor: 5.103

10.  Genetic analysis of human immunodeficiency virus type 1 integrase and the U3 att site: unusual phenotype of mutants in the zinc finger-like domain.

Authors:  T Masuda; V Planelles; P Krogstad; I S Chen
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103
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