Ran Xu1, Xiaokun Zhao, Zhaohui Zhong, Lei Zhang. 1. Department of Urology, The Second Xiangya Hospital, Central South University, 410011 Changsha, Hunan, People’s Republic of China.
Abstract
OBJECTIVE:Bowel preparation (BP) is performed routinely before intestinal surgery to reduce the risk of postoperative infectious complications. We studied the effect of BP on patients who underwentradical cystectomy and ileal conduit surgery. Our goal was to determine whether BP in these patients provided any benefits postoperatively. METHODS:Between Match 2006 and January 2009, 86 patients scheduled for radical cystectomy and ileal conduit were randomized to preoperative BP (group A) or surgery without BP (group B). Outcomes studied included operative time, recovery of patient and surgical complications. RESULTS:Eighty-six patients were included in the study, 47 in group A and 39 in group B. All surgeries were performed successfully using ileum. Postoperative complications were documented in 5 and 6 patients in groups A and B, respectively. Anastomotic leak occurred in 1 patient in group A, leading to multiple organ dysfunction and sepsis, with a fatal outcome. One case of ileus and three wound infections were also seen in group A. In group B, wound infection and ileus occurred in two patients each, anastomotic leak developed in 1 patient resulting to reoperation and one patient died from pulmonary embolism. No statistical difference in the frequency of complications and recovery of patient was observed between the 2 groups. CONCLUSIONS: Our results suggest that no advantage is gained by preoperative BP in radical cystectomy and ileal conduit.
RCT Entities:
OBJECTIVE: Bowel preparation (BP) is performed routinely before intestinal surgery to reduce the risk of postoperative infectious complications. We studied the effect of BP on patients who underwent radical cystectomy and ileal conduit surgery. Our goal was to determine whether BP in these patients provided any benefits postoperatively. METHODS: Between Match 2006 and January 2009, 86 patients scheduled for radical cystectomy and ileal conduit were randomized to preoperative BP (group A) or surgery without BP (group B). Outcomes studied included operative time, recovery of patient and surgical complications. RESULTS: Eighty-six patients were included in the study, 47 in group A and 39 in group B. All surgeries were performed successfully using ileum. Postoperative complications were documented in 5 and 6 patients in groups A and B, respectively. Anastomotic leak occurred in 1 patient in group A, leading to multiple organ dysfunction and sepsis, with a fatal outcome. One case of ileus and three wound infections were also seen in group A. In group B, wound infection and ileus occurred in two patients each, anastomotic leak developed in 1 patient resulting to reoperation and one patient died from pulmonary embolism. No statistical difference in the frequency of complications and recovery of patient was observed between the 2 groups. CONCLUSIONS: Our results suggest that no advantage is gained by preoperative BP in radical cystectomy and ileal conduit.
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