Literature DB >> 20384910

Integrated DNA and fingerprint analyses in the identification of 60-year-old mummified human remains discovered in an Alaskan glacier.

Odile M Loreille1, Ryan L Parr, Kevin A McGregor, Colleen M Fitzpatrick, Chriss Lyon, Dongya Y Yang, Camilla F Speller, Michael R Grimm, Michael J Grimm, Jodi A Irwin, Edward M Robinson.   

Abstract

This report describes the identification of a merchant mariner who perished in 1948 when Northwest Airlines Flight 4422, a DC-4 carrying 24 seamen and six crew members crashed into Mount Sanford, Alaska. Fifty-one years later, a human forearm and hand were found close by the wreckage of the plane, prompting identification efforts using DNA and fingerprints. There were significant challenges to both the fingerprint and DNA analyses. The hand was badly desiccated, making fingerprint friction-ridge detail almost invisible and the remains had been embalmed upon discovery, making DNA amplification difficult. We present the results of an interdisciplinary approach that successfully addressed these challenges and ultimately led to the identification of the remains. These efforts relied on efficient fingerprint rejuvenation and imaging techniques that improved print resolution, as well as new DNA extraction techniques optimized for aggressively embalmed remains.

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Year:  2010        PMID: 20384910     DOI: 10.1111/j.1556-4029.2010.01356.x

Source DB:  PubMed          Journal:  J Forensic Sci        ISSN: 0022-1198            Impact factor:   1.832


  7 in total

1.  Effective removal of co-purified inhibitors from extracted DNA samples using synchronous coefficient of drag alteration (SCODA) technology.

Authors:  Sarah Schmedes; Pamela Marshall; Jonathan L King; Bruce Budowle
Journal:  Int J Legal Med       Date:  2012-12-20       Impact factor: 2.686

2.  Assessment of the role of DNA repair in damaged forensic samples.

Authors:  Angie Ambers; Meredith Turnbough; Robert Benjamin; Jonathan King; Bruce Budowle
Journal:  Int J Legal Med       Date:  2014-05-03       Impact factor: 2.686

3.  The effect of chemical compromise on the recovery of DNA from skeletonized human remains: A study of three World War II era incidents recovered from tropical locations.

Authors:  Suni M Edson
Journal:  Forensic Sci Med Pathol       Date:  2019-11-12       Impact factor: 2.007

4.  A novel, 4-h DNA extraction method for STR typing of casework bone samples.

Authors:  Laila Hasap; Wilaiwan Chotigeat; Jintana Pradutkanchana; Uraporn Vongvatcharanon; Thitika Kitpipit; Phuvadol Thanakiatkrai
Journal:  Int J Legal Med       Date:  2020-01-02       Impact factor: 2.686

5.  Assessment of impact of DNA extraction methods on analysis of human remain samples on massively parallel sequencing success.

Authors:  Xiangpei Zeng; Kyleen Elwick; Carrie Mayes; Maiko Takahashi; Jonathan L King; David Gangitano; Bruce Budowle; Sheree Hughes-Stamm
Journal:  Int J Legal Med       Date:  2018-10-19       Impact factor: 2.686

6.  Biological Sexing of a 4000-Year-Old Egyptian Mummy Head to Assess the Potential of Nuclear DNA Recovery from the Most Damaged and Limited Forensic Specimens.

Authors:  Odile Loreille; Shashikala Ratnayake; Adam L Bazinet; Timothy B Stockwell; Daniel D Sommer; Nadin Rohland; Swapan Mallick; Philip L F Johnson; Pontus Skoglund; Anthony J Onorato; Nicholas H Bergman; David Reich; Jodi A Irwin
Journal:  Genes (Basel)       Date:  2018-03-01       Impact factor: 4.096

7.  Determination of materials present in skeletonized human remains and the associated DNA: Development of a GC/MS protocol.

Authors:  Suni M Edson; Marcel Roberts
Journal:  Forensic Sci Int Synerg       Date:  2019-08-10
  7 in total

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