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Literature DB >> 20384343

Update 1 of: Beta-strand mimetics.

Wendy A Loughlin¹, Joel D A Tyndall, Matthew P Glenn, Timothy A Hill, David P Fairlie.

Abstract

Mesh：

Substances：

Year: 2010 PMID： 20384343 DOI： 10.1021/cr900395y

Source DB: PubMed Journal: Chem Rev ISSN： 0009-2665 Impact factor: 60.622

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12 in total

Review 1. Small molecules, big targets: drug discovery faces the protein-protein interaction challenge.

Authors: Duncan E Scott; Andrew R Bayly; Chris Abell; John Skidmore
Journal: Nat Rev Drug Discov Date: 2016-04-11 Impact factor: 84.694

2. Ste24p Mediates Proteolysis of Both Isoprenylated and Non-prenylated Oligopeptides.

Authors: Emily R Hildebrandt; Buenafe T Arachea; Michael C Wiener; Walter K Schmidt
Journal: J Biol Chem Date: 2016-04-29 Impact factor: 5.157

3. The membrane anchor of the transcriptional activator SREBP is characterized by intrinsic conformational flexibility.

Authors: Rasmus Linser; Nicola Salvi; Rodolfo Briones; Petra Rovó; Bert L de Groot; Gerhard Wagner
Journal: Proc Natl Acad Sci U S A Date: 2015-09-21 Impact factor: 11.205

4. Extension of the CHARMM General Force Field to sulfonyl-containing compounds and its utility in biomolecular simulations.

Authors: Wenbo Yu; Xibing He; Kenno Vanommeslaeghe; Alexander D MacKerell
Journal: J Comput Chem Date: 2012-07-23 Impact factor: 3.376

5. Design, synthesis, and validation of a β-turn mimetic library targeting protein-protein and peptide-receptor interactions.

Authors: Landon R Whitby; Yoshio Ando; Vincent Setola; Peter K Vogt; Bryan L Roth; Dale L Boger
Journal: J Am Chem Soc Date: 2011-06-15 Impact factor: 15.419

6. Structural modifications of (Z)-3-(2-aminoethyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione that improve selectivity for inhibiting the proliferation of melanoma cells containing active ERK signaling.

Authors: Kwan-Young Jung; Ramin Samadani; Jay Chauhan; Kerrick Nevels; Jeremy L Yap; Jun Zhang; Shilpa Worlikar; Maryanna E Lanning; Lijia Chen; Mary Ensey; Sagar Shukla; Rosene Salmo; Geoffrey Heinzl; Caryn Gordon; Troy Dukes; Alexander D MacKerell; Paul Shapiro; Steven Fletcher
Journal: Org Biomol Chem Date: 2013-06-14 Impact factor: 3.876

Update 1 of: Beta-strand mimetics.

Review 1. Small molecules, big targets: drug discovery faces the protein-protein interaction challenge.

2. Ste24p Mediates Proteolysis of Both Isoprenylated and Non-prenylated Oligopeptides.

3. The membrane anchor of the transcriptional activator SREBP is characterized by intrinsic conformational flexibility.

4. Extension of the CHARMM General Force Field to sulfonyl-containing compounds and its utility in biomolecular simulations.

5. Design, synthesis, and validation of a β-turn mimetic library targeting protein-protein and peptide-receptor interactions.

6. Structural modifications of (Z)-3-(2-aminoethyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione that improve selectivity for inhibiting the proliferation of melanoma cells containing active ERK signaling.

7. N-Amination Converts Amyloidogenic Tau Peptides into Soluble Antagonists of Cellular Seeding.

Review 8. Protein Domain Mimics as Modulators of Protein-Protein Interactions.

9. Substituted imidazo[1,2-a]pyridines as β-strand peptidomimetics.

Review 10. Systematic Targeting of Protein-Protein Interactions.