The pharmacology of simulation: a conceptual framework to inform progress in simulation research.

This article presents a framework for the design and evaluation of simulation research to assist in developing evidence on which to base decisions about curriculum design and implementation. Drawing on basic concepts in pharmacology, the article describes simulation learning experiences as analogous to a drug treatment. This leads to consideration of simulation pharmacokinetics and pharmacodynamics, dose-time curves, dose-effect relationships, and drug-drug interactions.