Literature DB >> 20382190

Metagenomic analysis of bronchoalveolar lavage samples from patients with idiopathic interstitial pneumonia and its antagonic relation with Pneumocystis jirovecii colonization.

Vicente Friaza1, Carmen de la Horra, Mario J Rodríguez-Domínguez, José Martín-Juan, Rafael Cantón, Enrique J Calderón, Rosa Del Campo.   

Abstract

Idiopathic interstitial pneumonias are interstitial lung diseases of unknown etiology which prognosis is usually fatal. Microbiota associated to bronchoalveolar lavage from 20 patients with negative bacterial cultures was explored by 16S-rDNA PCR-DGGE, showing a clearly negative relation among the presence of P. jirovecii and bacterial colonization. This is the first report of in vivo antagonistic relation among fungi and bacteria. Copyright (c) 2010 Elsevier B.V. All rights reserved.

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Year:  2010        PMID： 20382190     DOI： 10.1016/j.mimet.2010.03.026

Source DB:  PubMed          Journal:  J Microbiol Methods        ISSN： 0167-7012            Impact factor:   2.363


  16 in total

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8.  The impact of different methods of DNA extraction on microbial community measures of BALF samples based on metagenomic data.

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10.  The airway microbiota in cystic fibrosis: a complex fungal and bacterial community--implications for therapeutic management.

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