| Literature DB >> 20379957 |
Jun Ma1, Paul Whittaker, Amy C Keller, Eugene P Mazzola, Rahul S Pawar, Kevin D White, John H Callahan, Edward J Kennelly, Alexander J Krynitsky, Jeanne I Rader.
Abstract
One new cucurbitane-type triterpenoid glycoside, momordicoside U (1), together with five known cucurbitane-type triterpenoids and related glycosides, 3β,7 β,25-trihydroxycucurbita-5,23 (E)-dien-19-al (2), momordicine I (3), momordicine II (4), 3-hydroxycucurbita-5,24-dien-19-al-7,23-di-O-β-glucopyranoside (5), and kuguaglycoside G (6), were isolated from the whole plant of Momordica charantia. Their structures were determined by chemical and spectroscopic methods. Momordicoside U (1) was evaluated for insulin secretion activity in an in vitro insulin secretion assay and displayed moderate activity. © Georg Thieme Verlag KG Stuttgart · New York.Entities:
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Year: 2010 PMID： 20379957 DOI： 10.1055/s-0030-1249807
Source DB: PubMed Journal: Planta Med ISSN： 0032-0943 Impact factor: 3.352