Two new sesquiterpenoid tropolone glycosides, liriosmasides A (1) and B (2), along with two known compounds, secoxyloganin and oplopanpheside C, were isolated from a methanol extract of the roots of Liriosma ovata. The structures of 1 and 2 were elucidated by spectroscopic methods including 1D and 2D NMR and by high-resolution mass spectrometry involving an ultra-high-performance liquid chromatography-quadrupole-orbital ion trap mass spectrometric (UHPLC-Q-Orbitrap MS) method. Compound 1 showed weak inhibitory activity against HIV RNase H.
Two new sesquiterpenoidn class="Chemical">tropolone glycosides, liriosmasides A (1) and B (2), along with two known compounds, secoxyloganin and oplopanpheside C, were isolated from a methanol extract of the roots of Liriosma ovata. The structures of 1 and 2 were elucidated by spectroscopic methods including 1D and 2DNMR and by high-resolution mass spectrometry involving an ultra-high-performance liquid chromatography-quadrupole-orbital ion trap mass spectrometric (UHPLC-Q-Orbitrap MS) method. Compound 1 showed weak inhibitory activity against HIVRNase H.
Authors: Jun Ma; Paul Whittaker; Amy C Keller; Eugene P Mazzola; Rahul S Pawar; Kevin D White; John H Callahan; Edward J Kennelly; Alexander J Krynitsky; Jeanne I Rader Journal: Planta Med Date: 2010-04-08 Impact factor: 3.352
Authors: Michael A Parniak; Kyung-Lyum Min; Scott R Budihas; Stuart F J Le Grice; John A Beutler Journal: Anal Biochem Date: 2003-11-01 Impact factor: 3.365
Authors: Scott R Budihas; Inna Gorshkova; Sergei Gaidamakov; Antony Wamiru; Marion K Bona; Michael A Parniak; Robert J Crouch; James B McMahon; John A Beutler; Stuart F J Le Grice Journal: Nucleic Acids Res Date: 2005-03-01 Impact factor: 16.971