Literature DB >> 20371472

Transforming medicine via digital innovation.

Eric J Topol1.   

Abstract

The lack of plasticity of the medical profession and health care system in the face of new technology and information is about to be challenged on two major fronts in digital medicine: wireless technologies and genomics. These two areas have been characterized by unprecedented innovation and discovery at a breakneck pace. Whereas the 2000s saw the introduction of digital life-style devices, the 2010s will probably be known as the era of digital medical devices. These devices have exceptional promise for changing the future of medicine because of their ability to produce exquisitely detailed individual biological and physiological data.

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Mesh:

Year:  2010        PMID: 20371472      PMCID: PMC3756088          DOI: 10.1126/scitranslmed.3000484

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN: 1946-6234            Impact factor:   17.956


  5 in total

1.  The genomics gold rush.

Authors:  Eric J Topol; Sarah S Murray; Kelly A Frazer
Journal:  JAMA       Date:  2007-07-11       Impact factor: 56.272

2.  Rehospitalizations among patients in the Medicare fee-for-service program.

Authors:  Stephen F Jencks; Mark V Williams; Eric A Coleman
Journal:  N Engl J Med       Date:  2009-04-02       Impact factor: 91.245

3.  Genome-wide association studies and human disease: from trickle to flood.

Authors:  Peter M Visscher; Grant W Montgomery
Journal:  JAMA       Date:  2009-11-11       Impact factor: 56.272

4.  Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays.

Authors:  Radoje Drmanac; Andrew B Sparks; Matthew J Callow; Aaron L Halpern; Norman L Burns; Bahram G Kermani; Paolo Carnevali; Igor Nazarenko; Geoffrey B Nilsen; George Yeung; Fredrik Dahl; Andres Fernandez; Bryan Staker; Krishna P Pant; Jonathan Baccash; Adam P Borcherding; Anushka Brownley; Ryan Cedeno; Linsu Chen; Dan Chernikoff; Alex Cheung; Razvan Chirita; Benjamin Curson; Jessica C Ebert; Coleen R Hacker; Robert Hartlage; Brian Hauser; Steve Huang; Yuan Jiang; Vitali Karpinchyk; Mark Koenig; Calvin Kong; Tom Landers; Catherine Le; Jia Liu; Celeste E McBride; Matt Morenzoni; Robert E Morey; Karl Mutch; Helena Perazich; Kimberly Perry; Brock A Peters; Joe Peterson; Charit L Pethiyagoda; Kaliprasad Pothuraju; Claudia Richter; Abraham M Rosenbaum; Shaunak Roy; Jay Shafto; Uladzislau Sharanhovich; Karen W Shannon; Conrad G Sheppy; Michel Sun; Joseph V Thakuria; Anne Tran; Dylan Vu; Alexander Wait Zaranek; Xiaodi Wu; Snezana Drmanac; Arnold R Oliphant; William C Banyai; Bruce Martin; Dennis G Ballinger; George M Church; Clifford A Reid
Journal:  Science       Date:  2009-11-05       Impact factor: 47.728

Review 5.  Finding the missing heritability of complex diseases.

Authors:  Teri A Manolio; Francis S Collins; Nancy J Cox; David B Goldstein; Lucia A Hindorff; David J Hunter; Mark I McCarthy; Erin M Ramos; Lon R Cardon; Aravinda Chakravarti; Judy H Cho; Alan E Guttmacher; Augustine Kong; Leonid Kruglyak; Elaine Mardis; Charles N Rotimi; Montgomery Slatkin; David Valle; Alice S Whittemore; Michael Boehnke; Andrew G Clark; Evan E Eichler; Greg Gibson; Jonathan L Haines; Trudy F C Mackay; Steven A McCarroll; Peter M Visscher
Journal:  Nature       Date:  2009-10-08       Impact factor: 49.962

  5 in total
  24 in total

1.  Digital technology in cardiac care.

Authors:  Alexandra King; Valentin Fuster
Journal:  Nat Rev Cardiol       Date:  2010-04       Impact factor: 32.419

Review 2.  Direct-to-consumer personalized genomic testing.

Authors:  Cinnamon S Bloss; Burcu F Darst; Eric J Topol; Nicholas J Schork
Journal:  Hum Mol Genet       Date:  2011-08-09       Impact factor: 6.150

Review 3.  Precision medicine in chronic disease management: The multiple sclerosis BioScreen.

Authors:  Pierre-Antoine Gourraud; Roland G Henry; Bruce A C Cree; Jason C Crane; Antoine Lizee; Marram P Olson; Adam V Santaniello; Esha Datta; Alyssa H Zhu; Carolyn J Bevan; Jeffrey M Gelfand; Jennifer S Graves; Douglas S Goodin; Ari J Green; H-Christian von Büdingen; Emmanuelle Waubant; Scott S Zamvil; Elizabeth Crabtree-Hartman; Sarah Nelson; Sergio E Baranzini; Stephen L Hauser
Journal:  Ann Neurol       Date:  2014-10-14       Impact factor: 10.422

4.  Design and evaluation of a wireless electronic health records system for field care in mass casualty settings.

Authors:  L A Lenert; D Kirsh; W G Griswold; C Buono; J Lyon; R Rao; T C Chan
Journal:  J Am Med Inform Assoc       Date:  2011-06-27       Impact factor: 4.497

Review 5.  Integrated Genomic Medicine: A Paradigm for Rare Diseases and Beyond.

Authors:  N J Schork; K Nazor
Journal:  Adv Genet       Date:  2017-07-25       Impact factor: 1.944

6.  Warning Symptoms Are Associated With Survival From Sudden Cardiac Arrest.

Authors:  Eloi Marijon; Audrey Uy-Evanado; Florence Dumas; Nicole Karam; Kyndaron Reinier; Carmen Teodorescu; Kumar Narayanan; Karen Gunson; Jonathan Jui; Xavier Jouven; Sumeet S Chugh
Journal:  Ann Intern Med       Date:  2016-12-22       Impact factor: 25.391

Review 7.  Mobile technology and the digitization of healthcare.

Authors:  Sanjeev P Bhavnani; Jagat Narula; Partho P Sengupta
Journal:  Eur Heart J       Date:  2016-02-11       Impact factor: 29.983

8.  Genomic information as a behavioral health intervention: can it work?

Authors:  Cinnamon S Bloss; Lisa Madlensky; Nicholas J Schork; Eric J Topol
Journal:  Per Med       Date:  2011-11       Impact factor: 2.512

9.  The n-of-1 clinical trial: the ultimate strategy for individualizing medicine?

Authors:  Elizabeth O Lillie; Bradley Patay; Joel Diamant; Brian Issell; Eric J Topol; Nicholas J Schork
Journal:  Per Med       Date:  2011-03       Impact factor: 2.512

10.  Calling Biomarkers in Milk Using a Protein Microarray on Your Smartphone.

Authors:  Susann K J Ludwig; Christian Tokarski; Stefan N Lang; Leendert A van Ginkel; Hongying Zhu; Aydogan Ozcan; Michel W F Nielen
Journal:  PLoS One       Date:  2015-08-26       Impact factor: 3.240

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