Literature DB >> 20356723

Decoding the function of nuclear long non-coding RNAs.

Ling-Ling Chen1, Gordon G Carmichael.   

Abstract

Long non-coding RNAs (lncRNAs) are mRNA-like, non-protein-coding RNAs that are pervasively transcribed throughout eukaryotic genomes. Rather than silently accumulating in the nucleus, many of these are now known or suspected to play important roles in nuclear architecture or in the regulation of gene expression. In this review, we highlight some recent progress in how lncRNAs regulate these important nuclear processes at the molecular level. Copyright 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 20356723      PMCID: PMC2916961          DOI: 10.1016/j.ceb.2010.03.003

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN: 0955-0674            Impact factor:   8.382


  55 in total

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Review 3.  Gene regulation by SINES and inosines: biological consequences of A-to-I editing of Alu element inverted repeats.

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Journal:  Nature       Date:  2009-02-01       Impact factor: 49.962

6.  An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles.

Authors:  Christine M Clemson; John N Hutchinson; Sergio A Sara; Alexander W Ensminger; Archa H Fox; Andrew Chess; Jeanne B Lawrence
Journal:  Mol Cell       Date:  2009-02-12       Impact factor: 17.970

7.  MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles.

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10.  B2 RNA and Alu RNA repress transcription by disrupting contacts between RNA polymerase II and promoter DNA within assembled complexes.

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  102 in total

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Journal:  Tumour Biol       Date:  2015-05-02

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5.  Tumor-specific silencing of COPZ2 gene encoding coatomer protein complex subunit ζ 2 renders tumor cells dependent on its paralogous gene COPZ1.

Authors:  Michael Shtutman; Mirza Baig; Elina Levina; Gregory Hurteau; Chang-Uk Lim; Eugenia Broude; Mikhail Nikiforov; Timothy T Harkins; C Steven Carmack; Ye Ding; Felix Wieland; Ralph Buttyan; Igor B Roninson
Journal:  Proc Natl Acad Sci U S A       Date:  2011-07-11       Impact factor: 11.205

6.  A novel long non-coding RNA, lncKBTBD10, involved in bovine skeletal muscle myogenesis.

Authors:  Mingming Chen; Xin Li; Xiaojuan Zhang; Yan Li; Junxing Zhang; Minhui Liu; Linlin Zhang; Xiangbin Ding; Xinfeng Liu; Hong Guo
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7.  Computational analysis of functional long noncoding RNAs reveals lack of peptide-coding capacity and parallels with 3' UTRs.

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8.  Expression profile of altered long non-coding RNAs in patients with HBV-associated hepatocellular carcinoma.

Authors:  Yan-Feng Pan; Tao Qin; Lei Feng; Zu-Jiang Yu
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9.  RNA splicing control: yet another gene regulatory role for long nuclear noncoding RNAs.

Authors:  Xinying Zong; Vidisha Tripathi; Kannanganattu V Prasanth
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10.  A novel RNA motif mediates the strict nuclear localization of a long noncoding RNA.

Authors:  Bing Zhang; Lalith Gunawardane; Farshad Niazi; Fereshteh Jahanbani; Xin Chen; Saba Valadkhan
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