Literature DB >> 20350944

Madurella mycetomatis is not susceptible to the echinocandin class of antifungal agents.

Wendy W J van de Sande1, Ahmed H Fahal, Irma A J M Bakker-Woudenberg, Alex van Belkum.   

Abstract

Eumycetoma caused by Madurella mycetomatis is treated surgically and with high doses of ketoconazole. Therapeutic responses are poor, and recurrent infections are common. In search of therapeutic alternatives in the treatment of mycetoma, we determined the in vitro susceptibilities of M. mycetomatis isolates against caspofungin, anidulafungin, and micafungin. As a comparator fungus, Aspergillus fumigatus was used. Minimal effective concentrations (MECs) and MICs were assessed and compared to those of ketoconazole. M. mycetomatis isolates were not susceptible to the echinocandins.

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Year:  2010        PMID： 20350944      PMCID： PMC2876377          DOI： 10.1128/AAC.01546-09

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

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Review 2.  Resistance to echinocandin-class antifungal drugs.

Authors:  David S Perlin
Journal:  Drug Resist Updat       Date:  2007-06-13       Impact factor: 18.500

3.  A microtiter-based fluorescence assay for (1,3)-beta-glucan synthases.

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Journal:  Anal Biochem       Date:  1997-06-15       Impact factor: 3.365

4.  Testing of the in vitro susceptibilities of Madurella mycetomatis to six antifungal agents by using the Sensititre system in comparison with a viability-based 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5- [(phenylamino)carbonyl]-2H-tetrazolium hydroxide (XTT) assay and a modified NCCLS method.

Authors:  Wendy W J van de Sande; Ad Luijendijk; Abdalla O A Ahmed; Irma A J M Bakker-Woudenberg; Alex van Belkum
Journal:  Antimicrob Agents Chemother       Date:  2005-04       Impact factor: 5.191

5.  Genotyping of Madurella mycetomatis by selective amplification of restriction fragments (amplified fragment length polymorphism) and subtype correlation with geographical origin and lesion size.

Authors:  Wendy W J van de Sande; Roy Gorkink; Guus Simons; Alewijn Ott; Abdalla O A Ahmed; Henri Verbrugh; Alex van Belkum
Journal:  J Clin Microbiol       Date:  2005-09       Impact factor: 5.948

6.  Cryptococcus neoformans resistance to echinocandins: (1,3)beta-glucan synthase activity is sensitive to echinocandins.

Authors:  Marybeth A Maligie; Claude P Selitrennikoff
Journal:  Antimicrob Agents Chemother       Date:  2005-07       Impact factor: 5.191

7.  The effects of antifungal agents to conidial and hyphal forms of Aspergillus fumigatus.

Authors:  Wendy W J van de Sande; Mehri Tavakol; Wim van Vianen; Irma A J M Bakker-Woudenberg
Journal:  Med Mycol       Date:  2010-02       Impact factor: 4.076

8.  In vitro activity of anidulafungin against selected clinically important mold isolates.

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Journal:  Antimicrob Agents Chemother       Date:  2004-05       Impact factor: 5.191

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Journal:  Antimicrob Agents Chemother       Date:  2004-07       Impact factor: 5.191

10.  Role for Fks1 in the intrinsic echinocandin resistance of Fusarium solani as evidenced by hybrid expression in Saccharomyces cerevisiae.

Authors:  Santosh K Katiyar; Thomas D Edlind
Journal:  Antimicrob Agents Chemother       Date:  2009-03-02       Impact factor: 5.191
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  13 in total

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Journal:  Antimicrob Agents Chemother       Date:  2019-12-20       Impact factor: 5.191

2.  Subcutaneous fungal infections.

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Authors:  Patricia E B Verwer; M L van Duijn; M Tavakol; Irma A J M Bakker-Woudenberg; Wendy W J van de Sande
Journal:  Antimicrob Agents Chemother       Date:  2011-12-27       Impact factor: 5.191

4.  Rapid and Robust Identification of the Agents of Black-Grain Mycetoma by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry.

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5.  In vitro susceptibility of Madurella mycetomatis to posaconazole and terbinafine.

Authors:  Alex van Belkum; Ahmed H Fahal; Wendy W J van de Sande
Journal:  Antimicrob Agents Chemother       Date:  2011-01-24       Impact factor: 5.191

6.  Novel Taxa Associated with Human Fungal Black-Grain Mycetomas: Emarellia grisea gen. nov., sp. nov., and Emarellia paragrisea sp. nov.

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Review 8.  The mycetoma knowledge gap: identification of research priorities.

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Review 9.  Mycetoma medical therapy.

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Review 10.  Mycetoma: An Update.

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Journal:  Indian J Dermatol       Date:  2017 Jul-Aug       Impact factor: 1.494
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