Literature DB >> 20336236

Diterpenoid alkaloids.

Feng-Peng Wang1, Qiao-Hong Chen, Xiao-Yu Liu.   

Abstract

The lasting attention that researchers have devoted to diterpenoid alkaloids is due to their various bioactivities and toxicities, structural complexity, and intriguing chemistry. From 1998 to the end of 2008, more than 300 new diterpenoid alkaloids were isolated from Nature. This review focuses on their structural relationships, and investigations into their chemical reactions, synthesis, and biological activities. A table that lists the names, plant sources, and structural types is given along with 363 references.

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Year:  2010        PMID： 20336236     DOI： 10.1039/b916679c

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  45 in total

1.  Cytotoxic esterified diterpenoid alkaloid derivatives with increased selectivity against a drug-resistant cancer cell line.

Authors:  Koji Wada; Emika Ohkoshi; Susan L Morris-Natschke; Kenneth F Bastow; Kuo-Hsiung Lee
Journal:  Bioorg Med Chem Lett       Date:  2011-11-11       Impact factor: 2.823

2.  A Copper-Mediated Conjugate Addition Approach to Analogues of Aconitine-Type Diterpenoid Alkaloids.

Authors:  Nicolle A Doering; Kevin G M Kou; Krissada Norseeda; Jack C Lee; Christopher J Marth; Gary M Gallego; Richmond Sarpong
Journal:  J Org Chem       Date:  2018-09-28       Impact factor: 4.354

3.  A Benzyne Insertion Approach to Hetisine-Type Diterpenoid Alkaloids: Synthesis of Cossonidine (Davisine).

Authors:  Kevin G M Kou; Jason J Pflueger; Toshihiro Kiho; Louis C Morrill; Ethan L Fisher; Kyle Clagg; Terry P Lebold; Jessica K Kisunzu; Richmond Sarpong
Journal:  J Am Chem Soc       Date:  2018-06-19       Impact factor: 15.419

4.  Cryptic and Stereospecific Hydroxylation, Oxidation, and Reduction in Platensimycin and Platencin Biosynthesis.

Authors:  Liao-Bin Dong; Xiao Zhang; Jeffrey D Rudolf; Ming-Rong Deng; Edward Kalkreuter; Alexis J Cepeda; Hans Renata; Ben Shen
Journal:  J Am Chem Soc       Date:  2019-02-19       Impact factor: 15.419

5.  Hydroxylation Metabolisms of Crassicauline A in Rats Under Toxic Dose.

Authors:  Xue Fan; Shan-Shan Yin; Xue-Jing Li; Kui Yang; Liang Xu; Ke Lan
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2017-10       Impact factor: 2.441

6.  Magnesiate Addition/Ring-Expansion Strategy To Access the 6-7-6 Tricyclic Core of Hetisine-Type C20-Diterpenoid Alkaloids.

Authors:  Jason J Pflueger; Louis C Morrill; Justine N deGruyter; Melecio A Perea; Richmond Sarpong
Journal:  Org Lett       Date:  2017-08-18       Impact factor: 6.005

7.  Total synthesis, relay synthesis, and structural confirmation of the C18-norditerpenoid alkaloid neofinaconitine.

Authors:  Yuan Shi; Jeremy T Wilmot; Lars Ulrik Nordstrøm; Derek S Tan; David Y Gin
Journal:  J Am Chem Soc       Date:  2013-09-16       Impact factor: 15.419

8.  Syntheses of Denudatine Diterpenoid Alkaloids: Cochlearenine, N-Ethyl-1α-hydroxy-17-veratroyldictyzine, and Paniculamine.

Authors:  Kevin G M Kou; Beryl X Li; Jack C Lee; Gary M Gallego; Terry P Lebold; Antonio G DiPasquale; Richmond Sarpong
Journal:  J Am Chem Soc       Date:  2016-08-22       Impact factor: 15.419

9.  Gallium(III)-catalyzed cycloisomerization approach to the diterpenoid alkaloids: construction of the core structure for the hetidines and hetisines.

Authors:  Amy M Hamlin; Felipe de Jesus Cortez; David Lapointe; Richmond Sarpong
Journal:  Angew Chem Int Ed Engl       Date:  2013-03-26       Impact factor: 15.336

10.  A Unifying Synthesis Approach to the C18-, C19-, and C20-Diterpenoid Alkaloids.

Authors:  Kevin G M Kou; Svitlana Kulyk; Christopher J Marth; Jack C Lee; Nicolle A Doering; Beryl X Li; Gary M Gallego; Terry P Lebold; Richmond Sarpong
Journal:  J Am Chem Soc       Date:  2017-09-20       Impact factor: 15.419
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