Visualization and detection-localization on computed tomographic images.

These studies investigated observers' ability to detect and locate highly visible liver lesions on computed tomographic (CT) images, manipulating both the lesion's location and polarity (brighter or darker than liver background). Visibility of a lesion is not sufficient to guarantee accurate localization. With clinical images, possible confusions between a lesion and coexisting normal structures (like blood vessels) is a serious constraint on observer performance.