Literature DB >> 2031517

Effectiveness of ofloxacin in the treatment of Chlamydia trachomatis and Neisseria gonorrhoeae cervical infection.

S Faro1, M G Martens, M Maccato, H A Hammill, S Roberts, G Riddle.   

Abstract

Forty patients with cervical infection caused by Chlamydia trachomatis were treated with ofloxacin (20) or doxycycline (20). Ofloxacin was successful in eradicating C. trachomatis from all 20 (100%) patients. Doxycycline was effective in 18 of 20 (90%) patients. Three patients had a concomitant cervical gonococcal infection. All three were successfully treated: one with ofloxacin and two with doxycycline. Ofloxacin, 300 mg, taken twice daily for 7 days, is effective in eradicating endocervical C. trachomatis infection.

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Year:  1991        PMID： 2031517     DOI： 10.1016/0002-9378(91)91476-d

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN： 0002-9378            Impact factor:   8.661


  8 in total

Review 1.  Ofloxacin. A reappraisal of its antimicrobial activity, pharmacology and therapeutic use.

Authors:  P A Todd; D Faulds
Journal:  Drugs       Date:  1991-11       Impact factor: 9.546

Review 2.  Concurrent gonococcal and chlamydial infection: how best to treat.

Authors:  A J Robinson; G L Ridgway
Journal:  Drugs       Date:  2000-04       Impact factor: 9.546

Review 3.  Chlamydia trachomatis in adolescents and adults. Clinical and economic implications.

Authors:  C A Marra; D M Patrick; R Reynolds; F Marra
Journal:  Pharmacoeconomics       Date:  1998-02       Impact factor: 4.981

4.  Persistence of Chlamydia trachomatis is induced by ciprofloxacin and ofloxacin in vitro.

Authors:  U Dreses-Werringloer; I Padubrin; B Jürgens-Saathoff; A P Hudson; H Zeidler; L Köhler
Journal:  Antimicrob Agents Chemother       Date:  2000-12       Impact factor: 5.191

Review 5.  Ofloxacin. A reappraisal of its use in the management of genitourinary tract infections.

Authors:  S V Onrust; H M Lamb; J A Balfour
Journal:  Drugs       Date:  1998-11       Impact factor: 9.546

6.  Periodic health examination, 1996 update: 2. Screening for chlamydial infections. Canadian Task Force on the Periodic Health Examination.

Authors:  H D Davies; E E Wang
Journal:  CMAJ       Date:  1996-06-01       Impact factor: 8.262

7.  Ofloxacin susceptibilities of 5,667 Neisseria gonorrhoeae strains isolated in Hong Kong.

Authors:  K M Kam; K K Lo; C F Lai; Y S Lee; C B Chan
Journal:  Antimicrob Agents Chemother       Date:  1993-09       Impact factor: 5.191

8.  Antibiotics for treating urogenital Chlamydia trachomatis infection in men and non-pregnant women.

Authors:  Carol Páez-Canro; Juan Pablo Alzate; Lina M González; Jorge Andres Rubio-Romero; Anne Lethaby; Hernando G Gaitán
Journal:  Cochrane Database Syst Rev       Date:  2019-01-25
  8 in total

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