Literature DB >> 20221842

Sex differences in alpha-adrenergic support of blood pressure.

Judith A M Schmitt1, Michael J Joyner, Nisha Charkoudian, B Gunnar Wallin, Emma C Hart.   

Abstract

We tested whether the inter-individual variability in alpha-adrenergic support of blood pressure plays a critical role in the sex differences in tonic support of blood pressure by the autonomic nervous system. Blockade of the alpha-adrenergic receptors was achieved via phentolamine and showed a smaller (P < 0.05) decrease in blood pressure in women compared to men, implying that alpha-adrenergic support of blood pressure is less in women than in men.

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Year:  2010        PMID: 20221842      PMCID: PMC3012387          DOI: 10.1007/s10286-010-0061-y

Source DB:  PubMed          Journal:  Clin Auton Res        ISSN: 0959-9851            Impact factor:   4.435


  18 in total

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Authors:  N Charkoudian
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10.  Sex differences in peripheral vascular adrenergic receptors.

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  23 in total

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4.  Sex differences in the contribution of blood pressure to acute changes in aortic augmentation index.

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Review 10.  New insights into the effects of age and sex on arterial baroreflex function at rest and during dynamic exercise in humans.

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