Victoria F Roche1. 1. School of Pharmacy and Health Professions, Creighton University Medical Center, Omaha, NE 68178, USA. roche@creighton.edu
Abstract
OBJECTIVE: To describe a receptor-based approach to promote learning about nonsteroidal anti-inflammatory drug (NSAID) chemistry, structure-activity relationships, and therapeutic decision-making. DESIGN: Three lessons on cyclooxygenase (COX) and NSAID chemistry, and NSAID therapeutic utility, were developed using text-based resources and primary medicinal chemistry and pharmacy practice literature. Learning tools were developed to assist students in content mastery. ASSESSMENT: Student learning was evaluated via performance on quizzes and examinations that measured understanding of COX and NSAID chemistry, and the application of that knowledge to therapeutic problem solving. CONCLUSION: Student performance on NSAID-focused quizzes and examinations documented the success of this approach.
OBJECTIVE: To describe a receptor-based approach to promote learning about nonsteroidal anti-inflammatory drug (NSAID) chemistry, structure-activity relationships, and therapeutic decision-making. DESIGN: Three lessons on cyclooxygenase (COX) and NSAID chemistry, and NSAID therapeutic utility, were developed using text-based resources and primary medicinal chemistry and pharmacy practice literature. Learning tools were developed to assist students in content mastery. ASSESSMENT: Student learning was evaluated via performance on quizzes and examinations that measured understanding of COX and NSAID chemistry, and the application of that knowledge to therapeutic problem solving. CONCLUSION: Student performance on NSAID-focused quizzes and examinations documented the success of this approach.
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