Literature DB >> 20213787

General and efficient copper-catalyzed three-component coupling reaction towards imidazoheterocycles: one-pot synthesis of alpidem and zolpidem.

Natalia Chernyak1, Vladimir Gevorgyan.   

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Year:  2010        PMID: 20213787      PMCID: PMC3516864          DOI: 10.1002/anie.200907291

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  22 in total

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Review 3.  Zolpidem: a review of its use in the management of insomnia.

Authors:  Tracy Swainston Harrison; Gillian M Keating
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4.  Enantioselective one-pot three-component synthesis of propargylamines.

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5.  Iron-catalyzed ligand-free three-component coupling reactions of aldehydes, terminal alkynes, and amines.

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6.  Highly efficient Grignard-type imine additions via C-H activation in water and under solvent-free conditions.

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7.  N-benzyl-2-(6,8-dichloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-N-(6-(7-nitrobenzo[c][1,2,5]oxadiazol-4-ylamino)hexyl)acetamide as a new fluorescent probe for peripheral benzodiazepine receptor and microglial cell visualization.

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8.  Influence of 6- or 8-substitution on the antiviral activity of 3-arylalkylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (CMV) and varicella-zoster virus (VZV): part II.

Authors:  Jean-Baptiste Véron; Hassan Allouchi; Cécile Enguehard-Gueiffier; Robert Snoeck; Graciela Andrei; Erik De Clercq; Alain Gueiffier
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9.  Structural requirements for eszopiclone and zolpidem binding to the gamma-aminobutyric acid type-A (GABAA) receptor are different.

Authors:  Susan M Hanson; Elaine V Morlock; Kenneth A Satyshur; Cynthia Czajkowski
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10.  Synthesis and biological evaluation of substituted [18F]imidazo[1,2-a]pyridines and [18F]pyrazolo[1,5-a]pyrimidines for the study of the peripheral benzodiazepine receptor using positron emission tomography.

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  20 in total

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2.  On the validity of Au-vinylidenes in the gold-catalyzed 1,2-migratory cycloisomerization of skipped propargylpyridines.

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Review 3.  α-Aminoazoles/azines: key reaction partners for multicomponent reactions.

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5.  Pyridine group assisted addition of diazo-compounds to imines in the 3-CC reaction of 2-aminopyridines, aldehydes, and diazo-compounds.

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6.  Selective, C-3 Friedel-Crafts acylation to generate functionally diverse, acetylated Imidazo[1,2-a]pyridine derivatives.

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7.  Catalyst free, C-3 functionalization of imidazo[1,2-a]pyridines to rapidly access new chemical space for drug discovery efforts.

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8.  Gold Catalysed Redox Synthesis of Imidazo[1,2-a]pyridine using Pyridine N-Oxide and Alkynes.

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9.  An overview of the key routes to the best selling 5-membered ring heterocyclic pharmaceuticals.

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