Literature DB >> 19177481

Iron-catalyzed ligand-free three-component coupling reactions of aldehydes, terminal alkynes, and amines.

Pinhua Li1, Yicheng Zhang, Lei Wang.   

Abstract

A tri-umph in many respects: The iron-catalyzed ligand-free, one-pot three-component coupling reactions of aldehydes, terminal alkynes, and amines in the presence of 4 A molecular sieves yields the corresponding propargylamines in good to excellent yields, displays a broad substrate scope, and is economical and environmentally friendly (see scheme).

Entities:  

Year:  2009        PMID： 19177481     DOI： 10.1002/chem.200802643

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  6 in total

1.  General and efficient copper-catalyzed three-component coupling reaction towards imidazoheterocycles: one-pot synthesis of alpidem and zolpidem.

Authors:  Natalia Chernyak; Vladimir Gevorgyan
Journal:  Angew Chem Int Ed Engl       Date:  2010-04-01       Impact factor: 15.336

2.  Efficient and General Synthesis of 3-Aminoindolines and 3-Aminoindoles via Copper-Catalyzed Three Component Coupling Reaction.

Authors:  Dmitri Chernyak; Natalia Chernyak; Vladimir Gevorgyan
Journal:  Adv Synth Catal       Date:  2010-04-19       Impact factor: 5.837

3.  Direct functionalization of (un)protected tetrahydroisoquinoline and isochroman under iron and copper catalysis: two metals, two mechanisms.

Authors:  Michael Ghobrial; Michael Schnürch; Marko D Mihovilovic
Journal:  J Org Chem       Date:  2011-10-05       Impact factor: 4.354

4.  Green synthesis of Au nanoparticles using an aqueous extract of Stachys lavandulifolia and their catalytic performance for alkyne/aldehyde/amine A3 coupling reactions.

Authors:  Hojat Veisi; Maliheh Farokhi; Mona Hamelian; Saba Hemmati
Journal:  RSC Adv       Date:  2018-11-14       Impact factor: 4.036

5.  ZnCl2 loaded TiO2 nanomaterial: an efficient green catalyst to one-pot solvent-free synthesis of propargylamines.

Authors:  Digambar B Bankar; Ranjit R Hawaldar; Sudhir S Arbuj; Mansur H Moulavi; Santosh T Shinde; Shrikant P Takle; Manish D Shinde; Dinesh P Amalnerkar; Kaluram G Kanade
Journal:  RSC Adv       Date:  2019-10-14       Impact factor: 4.036

6.  Immobilized Gold Nanoparticles Prepared from Gold(III)-Containing Ionic Liquids on Silica: Application to the Sustainable Synthesis of Propargylamines.

Authors:  Raquel Soengas; Yolanda Navarro; María José Iglesias; Fernando López-Ortiz
Journal:  Molecules       Date:  2018-11-14       Impact factor: 4.411
  6 in total

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