Literature DB >> 20195425

Statin induced myopathy presenting as mechanical musculoskeletal pain observed in two chiropractic patients.

Robert J Rodine1, Anthony C Tibbles, Peter Sy Kim, Neetan Alikhan.   

Abstract

Lipid lowering drugs, such as statins, are commonly used to treat approximately 10 million Canadians affected by hypercholesterolemia. The most commonly experienced side-effect of statin medication is muscle pain. Statin induced myopathy consists of a spectrum of myopathic disorders ranging from mild myalgia to fatal rhabdomyolysis. The following is a presentation of 2 cases of statin induced myopathy in patients presenting in a chiropractic setting. In addition, discussion will surround the mechanism, predisposing risk factors and frequency of statin induced myopathy while highlighting the role that chiropractors and other manual therapists may play in its recognition and management.

Entities:  

Keywords:  adverse events; chiropractic; myalgia; myopathy; myositis; rhabdomyolysis; statin

Year:  2010        PMID: 20195425      PMCID: PMC2829685     

Source DB:  PubMed          Journal:  J Can Chiropr Assoc        ISSN: 0008-3194


  43 in total

1.  ACC/AHA/NHLBI clinical advisory on the use and safety of statins.

Authors:  Richard C Pasternak; Sidney C Smith; C Noel Bairey-Merz; Scott M Grundy; James I Cleeman; Claude Lenfant
Journal:  J Am Coll Cardiol       Date:  2002-08-07       Impact factor: 24.094

2.  An assessment of statin safety by muscle experts.

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Journal:  Am J Cardiol       Date:  2006-02-09       Impact factor: 2.778

Review 3.  Statins and safety: applying the results of randomized trials to clinical practice.

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Journal:  Am J Cardiol       Date:  2003-09-15       Impact factor: 2.778

4.  Long-term effectiveness and safety of pravastatin in 9014 patients with coronary heart disease and average cholesterol concentrations: the LIPID trial follow-up.

Authors: 
Journal:  Lancet       Date:  2002-04-20       Impact factor: 79.321

Review 5.  Statin safety: an overview and assessment of the data--2005.

Authors:  Harold Bays
Journal:  Am J Cardiol       Date:  2006-02-08       Impact factor: 2.778

6.  Mortality and incidence of cancer during 10-year follow-up of the Scandinavian Simvastatin Survival Study (4S).

Authors:  Timo E Strandberg; Kalevi Pyörälä; Thomas J Cook; Lars Wilhelmsen; Ole Faergeman; Gudmundur Thorgeirsson; Terje R Pedersen; John Kjekshus
Journal:  Lancet       Date:  2004 Aug 28-Sep 3       Impact factor: 79.321

7.  Does statin therapy initiation increase the risk for myopathy? An observational study of 32,225 diabetic and nondiabetic patients.

Authors:  Gregory A Nichols; Carol E Koro
Journal:  Clin Ther       Date:  2007-08       Impact factor: 3.393

Review 8.  Primary evaluation and management of statin therapy complications.

Authors:  Dean A Seehusen; Chad A Asplund; Dawn R Johnson; Kevin A Horde
Journal:  South Med J       Date:  2006-03       Impact factor: 0.954

9.  Rhabdomyolysis: a case study exploring the possible side effect of lipid lowering medication by a HIV positive patient taking a protease inhibitor.

Authors:  Diana De Carvalho; Mark Citro; Anthony Tibbles
Journal:  J Can Chiropr Assoc       Date:  2008-12

10.  Primary prevention of cardiovascular mortality and events with statin treatments: a network meta-analysis involving more than 65,000 patients.

Authors:  Edward J Mills; Beth Rachlis; Ping Wu; Philip J Devereaux; Paul Arora; Dan Perri
Journal:  J Am Coll Cardiol       Date:  2008-11-25       Impact factor: 24.094

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  2 in total

1.  Curcumin improves atorvastatin-induced myotoxicity in rats: Histopathological and biochemical evidence.

Authors:  Said Said Elshama; Ayman El-Meghawry El-Kenawy; Hosam-Eldin Hussein Osman
Journal:  Int J Immunopathol Pharmacol       Date:  2016-08-09       Impact factor: 3.219

Review 2.  The Kaleidoscope Model of Integrative Healthcare as a collaborative paradigm for cardiology and chiropractic: a call to action.

Authors:  Daniel J Cohen; Steven Schulman; Charles S Masarsky; Marion Todres-Masarsky
Journal:  Integr Med Res       Date:  2018-02-08
  2 in total

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