Literature DB >> 20184337

Structure elucidation at the nanomole scale. 3. Phorbasides G-I from Phorbas sp.

Doralyn S Dalisay1, Tadeusz F Molinski.   

Abstract

Three new phorbasides (G-I), chlorocyclopropyl ene-yne macrolide glycosides, were isolated from the sponge Phorbas sp. in yields of 7-9.5 mug and fully characterized by MS, CD, and microcryoprobe NMR. The structures of the new compounds differ only in the nature of the sugar residues. The absolute configurations of the new compounds were correlated by ROESY and CD with the parent compounds phorbasides A and B.

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Year:  2010        PMID: 20184337      PMCID: PMC2859111          DOI: 10.1021/np1000297

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  13 in total

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