Literature DB >> 20162051

Analgesic and anti-inflammatory activities of Asparagus africanus root extract.

Hs Hassan1, A A Ahmadu, A S Hassan.   

Abstract

The methanolic extract of the roots of Asparagus africanus Lam (Liliaceae) which contains mainly saponins and carbohydrate showed significant analgesic and anti-inflammatory activities (P<0.05) in the tail-flick/hot-plate test and egg albumen-induced rat paw oedema tests that were comparable to the test drugs (morphine 20 mg/kg and indomethacin 50 mg/kg respectively). These results indicate that the extract possesses analgesic and anti-inflammatory properties.

Entities:  

Keywords:  Asparagus africanus; analgesic and anti-inflammatory activities; roots

Year:  2007        PMID: 20162051      PMCID: PMC2816601          DOI: 10.4314/ajtcam.v5i1.31252

Source DB:  PubMed          Journal:  Afr J Tradit Complement Altern Med        ISSN: 2505-0044


  9 in total

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2.  Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs.

Authors:  C A WINTER; E A RISLEY; G W NUSS
Journal:  Proc Soc Exp Biol Med       Date:  1962-12

3.  A review of the biological and pharmacological activities of saponins.

Authors:  M A Lacaille-Dubois; H Wagner
Journal:  Phytomedicine       Date:  1996-03       Impact factor: 5.340

4.  Studies on the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine.

Authors:  M Di Rosa; J P Giroud; D A Willoughby
Journal:  J Pathol       Date:  1971-05       Impact factor: 7.996

Review 5.  Nonsteroid antiinflammatory agents.

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Journal:  Fortschr Arzneimittelforsch       Date:  1966

6.  A new approach to practical acute toxicity testing.

Authors:  D Lorke
Journal:  Arch Toxicol       Date:  1983-12       Impact factor: 5.153

7.  Steroidal saponins from Asparagus africanus.

Authors:  A Debella; E Haslinger; O Kunert; G Michl; D Abebe
Journal:  Phytochemistry       Date:  1999-08       Impact factor: 4.072

8.  Antiprotozoal compounds from Asparagus africanus.

Authors:  H A Oketch-Rabah; S F Dossaji; S B Christensen; K Frydenvang; E Lemmich; C Cornett; C E Olsen; M Chen; A Kharazmi; T Theander
Journal:  J Nat Prod       Date:  1997-10       Impact factor: 4.050

9.  Ethiopian traditional herbal drugs. Part II: Antimicrobial activity of 63 medicinal plants.

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Journal:  J Ethnopharmacol       Date:  1993-06       Impact factor: 4.360

  9 in total
  8 in total

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Journal:  Phys Chem Earth (2002)       Date:  2022-09-21       Impact factor: 3.311

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Authors:  H S Hassan; M I Sule; A M Musa; K Y Musa; M S Abubakar; A S Hassan
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3.  Biochemical and toxicological effects of methanolic extract of Asparagus africanus Lam in Sprague-Dawley rats.

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4.  Nephroprotective Effect of Asparagus africanus Lam. Root Extract against Gentamicin-Induced Nephrotoxicity in Swiss Albino Mice.

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5.  In vitro antimicrobial activity of extracts from plants used traditionally in South Africa to treat tuberculosis and related symptoms.

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Journal:  Evid Based Complement Alternat Med       Date:  2013-03-05       Impact factor: 2.629

Review 6.  Traditional use of medicinal plants in south-central Zimbabwe: review and perspectives.

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Journal:  J Ethnobiol Ethnomed       Date:  2013-05-04       Impact factor: 2.733

7.  Analgesic and Antioxidant Activities of Stem Bark Extract and Fractions of Petersianthus macrocarpus.

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8.  A survey of ethnomedicinal plants used to treat cancer by traditional medicine practitioners in Zimbabwe.

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  8 in total

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