Literature DB >> 36161239

Medicinal plants used for the management of respiratory diseases in Zimbabwe: Review and perspectives potential management of COVID-19.

Elliot Nyagumbo1, William Pote2,3, Bridgett Shopo4,2, Trust Nyirenda5,6, Ignatius Chagonda7, Ruvimbo J Mapaya4, Fabian Maunganidze2,5, William N Mavengere2,8, Cephas Mawere8, Ian Mutasa2,3, Emmanuel Kademeteme3, Alfred Maroyi9, Tafadzwa Taderera10, Michael Bhebhe1,2.   

Abstract

Respiratory diseases have in the recent past become a health concern globally. More than 523 million cases of coronavirus disease (COVID19), a recent respiratory diseases have been reported, leaving more than 6 million deaths worldwide since the start of the pandemic. In Zimbabwe, respiratory infections have largely been managed using traditional (herbal) medicines, due to their low cost and ease of accessibility. This review highlights the plants' toxicological and pharmacological evaluation studies explored. It seeks to document plants that have been traditionally used in Zimbabwe to treat respiratory ailments within and beyond the past four decades. Extensive literature review based on published papers and abstracts retrieved from the online bibliographic databases, books, book chapters, scientific reports and theses available at Universities in Zimbabwe, were used in this study. From the study, there were at least 58 plant families comprising 160 medicinal plants widely distributed throughout the country. The Fabaceae family had the highest number of medicinal plant species, with a total of 21 species. A total of 12 respiratory ailments were reportedly treatable using the identified plants. From a total of 160 plants, colds were reportedly treatable with 56, pneumonia 53, coughs 34, chest pain and related conditions 29, asthma 25, tuberculosis and spots in lungs 22, unspecified respiratory conditions 20, influenza 13, bronchial problems 12, dyspnoea 7, sore throat and infections 5 and sinus clearing 1 plant. The study identified potential medicinal plants that can be utilised in future to manage respiratory infections.
© 2022 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Coronavirus disease 2019; Medicinal plants; Pharmacology; Respiratory disorders; Toxicology; Zimbabwe

Year:  2022        PMID: 36161239      PMCID: PMC9489988          DOI: 10.1016/j.pce.2022.103232

Source DB:  PubMed          Journal:  Phys Chem Earth (2002)        ISSN: 1474-7065            Impact factor:   3.311


  180 in total

Review 1.  The Genus Aloe: Phytochemistry and Therapeutic Uses Including Treatments for Gastrointestinal Conditions and Chronic Inflammation.

Authors:  I E Cock
Journal:  Prog Drug Res       Date:  2015

2.  Cembranolides from the stem bark of the southern African medicinal plant, Croton gratissimus (Euphorbiaceae).

Authors:  Dulcie A Mulholland; Moses K Langat; Neil R Crouch; Helen M Coley; Emily M Mutambi; Jean-Marc Nuzillard
Journal:  Phytochemistry       Date:  2010-06-11       Impact factor: 4.072

3.  Fresh ginger (Zingiber officinale) has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines.

Authors:  Jung San Chang; Kuo Chih Wang; Chia Feng Yeh; Den En Shieh; Lien Chai Chiang
Journal:  J Ethnopharmacol       Date:  2012-11-01       Impact factor: 4.360

4.  Structure and chemotherapeutical activity of a polyisoprenylated benzophenone from the stem bark of Garcinia huillensis.

Authors:  P Bakana; M Claeys; J Totté; L A Pieters; L Van Hoof; D A Van den Berghe; A J Vlietinck
Journal:  J Ethnopharmacol       Date:  1987 Sep-Oct       Impact factor: 4.360

Review 5.  The Genus Carissa: An Ethnopharmacological, Phytochemical and Pharmacological Review.

Authors:  Joseph Sakah Kaunda; Ying-Jun Zhang
Journal:  Nat Prod Bioprospect       Date:  2017-02-27

6.  Evaluation of α-amylase, lipase inhibition and in-vivo pharmacological activities of Eucalyptus camaladulensis Dehnh leaf extract.

Authors:  Anil Upreti; Bibek Byanju; Muna Fuyal; Apekshya Chhetri; Paras Pandey; Rajeswar Ranjitkar; Jyoti Joshi Bhatta; Bishnu Prasad Pandey
Journal:  J Tradit Complement Med       Date:  2018-07-29

7.  A cross-sectional study to determine the use of alternative medicines during pregnancy in the district hospitals in Manicaland, Zimbabwe.

Authors:  Liphapang Dimene; Mutseyekwa Fadzai; Jephat Chifamba; Gerald Nyakatawa; Carol Mahachi; Amos Marume; Michael Bhebhe; Tafadzwa Taderera
Journal:  Afr Health Sci       Date:  2020-03       Impact factor: 0.927

8.  Biological Activities of Heteropyxis natalensis Against Micro-Organisms Involved in Oral Infections.

Authors:  Cynthia J Henley-Smith; Francien S Botha; Ahmed A Hussein; Mpumelelo Nkomo; Debra Meyer; Namrita Lall
Journal:  Front Pharmacol       Date:  2018-04-10       Impact factor: 5.810

Review 9.  Citrus limon (Lemon) Phenomenon-A Review of the Chemistry, Pharmacological Properties, Applications in the Modern Pharmaceutical, Food, and Cosmetics Industries, and Biotechnological Studies.

Authors:  Marta Klimek-Szczykutowicz; Agnieszka Szopa; Halina Ekiert
Journal:  Plants (Basel)       Date:  2020-01-17

10.  The Effects of Combining Cancer Drugs with Compounds Isolated from Combretum zeyheri Sond. and Combretum platypetalum Welw. ex M.A. Lawson (Combretaceae) on the Viability of Jurkat T Cells and HL-60 Cells.

Authors:  Morris Wende; Simbarashe Sithole; Godloves Fru Chi; Marc Y Stevens; Stanley Mukanganyama
Journal:  Biomed Res Int       Date:  2021-01-18       Impact factor: 3.411

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