Literature DB >> 20161584

A Microfluidic Cartridge System for Multiplexed Clinical Analysis.

Walson Lawi1, Chris Wiita, Steven T Snyder, Fang Wei, David Wong, Pak Kin Wong, Joseph C Liao, David Haake, Vincent Gau.   

Abstract

Cartridge-based microfluidics is a promising technology for clinical diagnostics. By miniaturizing the fluid-handling processes required for genomic and proteomic analyses, reagent and specimen volume is minimized along with the size of the system. We demonstrate an automated microfluidic system capable of performing six multiplexed genomic and proteomic analyses simultaneously, by means of an integrated electrochemical sensor and embedded controls.

Entities:  

Year:  2009        PMID： 20161584      PMCID： PMC2808045          DOI： 10.1016/j.jala.2009.05.002

Source DB:  PubMed          Journal:  JALA Charlottesv Va        ISSN： 1535-5535


  8 in total

1.  An electrochemical detection scheme for identification of single nucleotide polymorphisms using hairpin-forming probes.

Authors:  Tony Jun Huang; Minghsun Liu; Linda D Knight; Wayne W Grody; Jeff F Miller; Chih-Ming Ho
Journal:  Nucleic Acids Res       Date:  2002-06-15       Impact factor: 16.971

2.  Use of electrochemical DNA biosensors for rapid molecular identification of uropathogens in clinical urine specimens.

Authors:  Joseph C Liao; Mitra Mastali; Vincent Gau; Marc A Suchard; Annette K Møller; David A Bruckner; Jane T Babbitt; Yang Li; Jeffrey Gornbein; Elliot M Landaw; Edward R B McCabe; Bernard M Churchill; David A Haake
Journal:  J Clin Microbiol       Date:  2006-02       Impact factor: 5.948

3.  Development of an advanced electrochemical DNA biosensor for bacterial pathogen detection.

Authors:  Joseph C Liao; Mitra Mastali; Yang Li; Vincent Gau; Marc A Suchard; Jane Babbitt; Jeffrey Gornbein; Elliot M Landaw; Edward R B McCabe; Bernard M Churchill; David A Haake
Journal:  J Mol Diagn       Date:  2007-04       Impact factor: 5.568

4.  Optimal probe length and target location for electrochemical detection of selected uropathogens at ambient temperature.

Authors:  Mitra Mastali; Jane T Babbitt; Yang Li; Elliot M Landaw; Vincent Gau; Bernard M Churchill; David A Haake
Journal:  J Clin Microbiol       Date:  2008-06-18       Impact factor: 5.948

5.  Rapid, species-specific detection of uropathogen 16S rDNA and rRNA at ambient temperature by dot-blot hybridization and an electrochemical sensor array.

Authors:  Chien-Pin Sun; Joseph C Liao; Yao-Hua Zhang; Vincent Gau; Mitra Mastali; Jane T Babbitt; Warren S Grundfest; Bernard M Churchill; Edward R B McCabe; David A Haake
Journal:  Mol Genet Metab       Date:  2004-12-13       Impact factor: 4.797

6.  A MEMS based amperometric detector for E. coli bacteria using self-assembled monolayers.

Authors:  J J Gau; E H Lan; B Dunn; C M Ho; J C Woo
Journal:  Biosens Bioelectron       Date:  2001-12       Impact factor: 10.618

Review 7.  Electrochemical molecular analysis without nucleic acid amplification.

Authors:  Vincent Gau; Shu-Ching Ma; Hua Wang; Joni Tsukuda; John Kibler; David A Haake
Journal:  Methods       Date:  2005-10-04       Impact factor: 3.608

8.  Electrochemical detection of low-copy number salivary RNA based on specific signal amplification with a hairpin probe.

Authors:  Fang Wei; Jianghua Wang; Wei Liao; Bernhard G Zimmermann; David T Wong; Chih-Ming Ho
Journal:  Nucleic Acids Res       Date:  2008-05-17       Impact factor: 16.971
  8 in total
  10 in total

1.  A biosensor platform for rapid antimicrobial susceptibility testing directly from clinical samples.

Authors:  Kathleen E Mach; Ruchika Mohan; Ellen Jo Baron; Mei-Chiung Shih; Vincent Gau; Pak Kin Wong; Joseph C Liao
Journal:  J Urol       Date:  2010-11-12       Impact factor: 7.450

2.  Electrothermal Fluid Manipulation of High-Conductivity Samples for Laboratory Automation Applications.

Authors:  Mandy L Y Sin; Vincent Gau; Joseph C Liao; Pak Kin Wong
Journal:  JALA Charlottesv Va       Date:  2010-12-31

3.  Hybrid electrokinetic manipulation in high-conductivity media.

Authors:  Jian Gao; Mandy L Y Sin; Tingting Liu; Vincent Gau; Joseph C Liao; Pak Kin Wong
Journal:  Lab Chip       Date:  2011-04-12       Impact factor: 6.799

4.  In situ electrokinetic enhancement for self-assembled-monolayer-based electrochemical biosensing.

Authors:  Mandy L Y Sin; Tingting Liu; Jeffrey D Pyne; Vincent Gau; Joseph C Liao; Pak Kin Wong
Journal:  Anal Chem       Date:  2012-03-06       Impact factor: 6.986

5.  Biosensor diagnosis of urinary tract infections: a path to better treatment?

Authors:  Kathleen E Mach; Pak Kin Wong; Joseph C Liao
Journal:  Trends Pharmacol Sci       Date:  2011-03-31       Impact factor: 14.819

6.  Rapid antimicrobial susceptibility testing with electrokinetics enhanced biosensors for diagnosis of acute bacterial infections.

Authors:  Tingting Liu; Yi Lu; Vincent Gau; Joseph C Liao; Pak Kin Wong
Journal:  Ann Biomed Eng       Date:  2014-06-03       Impact factor: 3.934

7.  System Integration - A Major Step toward Lab on a Chip.

Authors:  Mandy Ly Sin; Jian Gao; Joseph C Liao; Pak Kin Wong
Journal:  J Biol Eng       Date:  2011-05-25       Impact factor: 4.355

Review 8.  Multiplexed Point-of-Care Testing - xPOCT.

Authors:  Can Dincer; Richard Bruch; André Kling; Petra S Dittrich; Gerald A Urban
Journal:  Trends Biotechnol       Date:  2017-04-26       Impact factor: 19.536

9.  Direct-from-specimen microbial growth inhibition spectrums under antibiotic exposure and comparison to conventional antimicrobial susceptibility testing.

Authors:  Jade Chen; Su Su Soe San; Amelia Kung; Michael Tomasek; Dakai Liu; William Rodgers; Vincent Gau
Journal:  PLoS One       Date:  2022-02-16       Impact factor: 3.240

Review 10.  Recent advances in application of biosensors in tissue engineering.

Authors:  Anwarul Hasan; Md Nurunnabi; Mahboob Morshed; Arghya Paul; Alessandro Polini; Tapas Kuila; Moustafa Al Hariri; Yong-kyu Lee; Ayad A Jaffa
Journal:  Biomed Res Int       Date:  2014-08-06       Impact factor: 3.411
  10 in total

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