Literature DB >> 20158684

The status of massive transfusion protocols in United States trauma centers: massive transfusion or massive confusion?

Kevin M Schuster1, Kimberly A Davis, Felix Y Lui, Linda L Maerz, Lewis J Kaplan.   

Abstract

BACKGROUND: Massive transfusion protocol (MTP) utilization and makeup is unknown. STUDY DESIGN AND METHODS: A Web-based survey was sent to members of the Eastern Association for the Surgery of Trauma and published in the American Association for the Surgery of Trauma newsletter. Comparisons were made with chi-square and logistic regression.
RESULTS: A total of 186 surgeons and 59 center directors responded. To avoid bias, directors' responses are reported. Sixty percent annually admit more than 1500 patients. Sixty-seven percent had in-house attending coverage and 85% had a MTP. Presence of a MTP was not predicted by institution size, level, residency status, or admissions. Sixty-five percent of MTPs had been in place less than 5 years with 18% less than 1 year. Designs varied: 23% had one batch of components, 25% had two or three, 41% had more than three, and 11% did not use batches. Only 62% of first batches contained fresh-frozen plasma (FFP). In the second batch 98% had FFP. All third boxes had FFP. A ratio of FFP : red blood cells (RBCs) of less than 1 in the first batch predicted a ratio less than 1 in the second batch (p = 0.013). Twenty-seven percent had blood stored in the emergency department and 14% in the operating room. Twenty-four percent of MTPs autoactivate and 80% are trauma surgeon activated, 66% by the anesthesia staff, 32% by other surgeons, and 17% by the blood bank. Trauma surgeons activate the MTP most.
CONCLUSION: Most centers have a MTP. Protocols are variable and new, and half have a 1:1 FFP : RBC ratio. Protocols with fewer initial units of FFP compared to RBCs maintain this.

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Year:  2010        PMID: 20158684     DOI: 10.1111/j.1537-2995.2010.02587.x

Source DB:  PubMed          Journal:  Transfusion        ISSN: 0041-1132            Impact factor:   3.157


  27 in total

1.  Association between frequency of blood tests and mortality rate in patients undergoing massive blood transfusion: a multicenter study in five regions of China.

Authors:  Yang Sun; Jiang-Cun Yang; Qian-Li Dang; Ping Chen; Ting Ma; Cui-Xiang Xu
Journal:  Int J Clin Exp Med       Date:  2015-05-15

2.  Balanced ratio of plasma to packed red blood cells improves outcomes in massive transfusion: A large multicenter study.

Authors:  Jiang-Cun Yang; Cui-Xiang Xu; Yang Sun; Qian-Li Dang; Ling Li; Yong-Gang Xu; Yao-Jun Song; Hong Yan
Journal:  Exp Ther Med       Date:  2015-04-30       Impact factor: 2.447

3.  The plasma and platelet are important in reducing the mortality in surgical massive blood transfusion: a large multicenter study in China.

Authors:  Zhan-Kui Jin; Yang Sun; Qian-Li Dang; Li-Jie Zhang; Ling Li; Yong-Gang Xu; Hong-Nan Chen; Cui-Xiang Xu; Yao-Jun Song; Jiang-Cun Yang
Journal:  Int J Clin Exp Med       Date:  2015-01-15

Review 4.  The initial trauma center fluid management of penetrating injury: a systematic review.

Authors:  Nicole M Tapia; James Suliburk; Kenneth L Mattox
Journal:  Clin Orthop Relat Res       Date:  2013-12       Impact factor: 4.176

5.  Association Between Ratio of Fresh Frozen Plasma to Red Blood Cells During Massive Transfusion and Survival Among Patients Without Traumatic Injury.

Authors:  Tomaz Mesar; Andreas Larentzakis; Walter Dzik; Yuchiao Chang; George Velmahos; Daniel Dante Yeh
Journal:  JAMA Surg       Date:  2017-06-01       Impact factor: 14.766

6.  A preoperative risk score for transfusion in infrarenal endovascular aneurysm repair to avoid type and cross.

Authors:  Thomas F X O'Donnell; Katie E Shean; Sarah E Deery; Thomas C F Bodewes; Mark C Wyers; Kerry L O'Brien; Robina Matyal; Marc L Schermerhorn
Journal:  J Vasc Surg       Date:  2017-07-26       Impact factor: 4.268

Review 7.  Massive transfusion protocols for patients with substantial hemorrhage.

Authors:  Pampee P Young; Bryan A Cotton; Lawrence T Goodnough
Journal:  Transfus Med Rev       Date:  2011-06-12

8.  Reduction of Fresh Frozen Plasma Requirements by Perioperative Point-of-Care Coagulation Management with Early Calculated Goal-Directed Therapy.

Authors:  Klaus Görlinger; Dietmar Fries; Daniel Dirkmann; Christian F Weber; Alexander A Hanke; Herbert Schöchl
Journal:  Transfus Med Hemother       Date:  2012-03-08       Impact factor: 3.747

9.  Investigation of the current situation of massive blood transfusion in different surgical departments: a large multicenter study in China.

Authors:  Yang Sun; Zhan-Kui Jin; Cui-Xiang Xu; Qian-Li Dang; Li-Jie Zhang; Hong-Nan Chen; Yao-Jun Song; Jiang-Cun Yang
Journal:  Int J Clin Exp Med       Date:  2015-06-15

10.  The treatment of traumatic shock: recent advances and unresolved questions.

Authors:  K Sisak; D Dewar; N Butcher; K King; J Evans; M Miller; O Yoshino; P Harrigan; C Bendinelli; Z J Balogh
Journal:  Eur J Trauma Emerg Surg       Date:  2011-09-02       Impact factor: 3.693

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