Literature DB >> 25785095

The plasma and platelet are important in reducing the mortality in surgical massive blood transfusion: a large multicenter study in China.

Zhan-Kui Jin1, Yang Sun2, Qian-Li Dang3, Li-Jie Zhang2, Ling Li4, Yong-Gang Xu5, Hong-Nan Chen4, Cui-Xiang Xu6, Yao-Jun Song2, Jiang-Cun Yang2.   

Abstract

OBJECTIVE: The aim of this study was to learn the current situation of surgical massive transfusion of death and survival groups in China, which could provide the basis for the formulation of guidelines on massive transfusion.
METHODS: A multicenter retrospective research for the application status of blood constituents during massive blood transfusion was conducted, the differences of fresh frozen plasma and platelet application between death group and survival group were compared, and the transfusion volume and the distribution of other blood constituents were analyses at different periods of time when red blood cells are infused between death group and survival group.
RESULTS: The patients with fresh frozen plasma compare the patients with red blood cell was 1:1-2 during massive transfusion, while the dosage of platelet and cryocepitate were transfused very small. Results showed that the average amount of platelet and plasma in death group was significantly lower than those in survival group.
CONCLUSION: During massive transfusion, clinicians in 20 Chinese hospitals paid more attention to the infusion of fresh frozen plasma while making the infusion of red blood cells. However, they paid little attention to the supplement of platelet and cryocepitate. The average quantity of plasma and platelet in survival group were also higher than those in death group.

Entities:  

Keywords:  Massive transfusion; blood constituents; plasma; platelet

Year:  2015        PMID: 25785095      PMCID: PMC4358550     

Source DB:  PubMed          Journal:  Int J Clin Exp Med        ISSN: 1940-5901


  16 in total

1.  Early coagulopathy predicts mortality in trauma.

Authors:  Jana B A MacLeod; Mauricio Lynn; Mark G McKenney; Stephen M Cohn; Mary Murtha
Journal:  J Trauma       Date:  2003-07

Review 2.  ABC of transfusion. Massive blood transfusion.

Authors:  P E Hewitt; S J Machin
Journal:  BMJ       Date:  1990-01-13

3.  Fresh-frozen plasma transfusion strategy in trauma with massive and ongoing bleeding. Common (sense) and sensibility.

Authors:  Anthony M-H Ho; Peter W Dion; Janice H H Yeung; Calvin S H Ng; Manoj K Karmakar; Lester A H Critchley; Timothy H Rainer; Chi Wai Cheung; Beng A Tay
Journal:  Resuscitation       Date:  2010-06-22       Impact factor: 5.262

4.  Massive transfusion practices around the globe and a suggestion for a common massive transfusion protocol.

Authors:  Debra L Malone; John R Hess; Abe Fingerhut
Journal:  J Trauma       Date:  2006-06

5.  Guidelines on the management of massive blood loss.

Authors:  D Stainsby; S MacLennan; D Thomas; J Isaac; P J Hamilton
Journal:  Br J Haematol       Date:  2006-12       Impact factor: 6.998

6.  Application status of blood constituents during massive blood transfusion in some regions of China.

Authors:  Jiang-Cun Yang; Yang Sun; Cui-Xiang Xu; Qian-Li Dang; Ling Li; Yong-Gang Xu; Yao-Jun Song; Hong Yan
Journal:  Int J Clin Exp Med       Date:  2014-07-15

7.  A high ratio of plasma and platelets to packed red blood cells in the first 6 hours of massive transfusion improves outcomes in a large multicenter study.

Authors:  Karen A Zink; Chitra N Sambasivan; John B Holcomb; Gary Chisholm; Martin A Schreiber
Journal:  Am J Surg       Date:  2009-05       Impact factor: 2.565

8.  The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital.

Authors:  Matthew A Borgman; Philip C Spinella; Jeremy G Perkins; Kurt W Grathwohl; Thomas Repine; Alec C Beekley; James Sebesta; Donald Jenkins; Charles E Wade; John B Holcomb
Journal:  J Trauma       Date:  2007-10

9.  Blood transfusion rates in the care of acute trauma.

Authors:  John J Como; Richard P Dutton; Thomas M Scalea; Bennett B Edelman; John R Hess
Journal:  Transfusion       Date:  2004-06       Impact factor: 3.157

Review 10.  Massive blood transfusions: the impact of Vietnam military data on modern civilian transfusion medicine.

Authors:  Ronald D Miller
Journal:  Anesthesiology       Date:  2009-06       Impact factor: 7.892

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  1 in total

1.  Investigation of the status quo of massive blood transfusion in China and a synopsis of the proposed guidelines for massive blood transfusion.

Authors:  Jiang-Cun Yang; Qiu-Shi Wang; Qian-Li Dang; Yang Sun; Cui-Xiang Xu; Zhan-Kui Jin; Ting Ma; Jing Liu
Journal:  Medicine (Baltimore)       Date:  2017-08       Impact factor: 1.889

  1 in total

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