Yang Sun1, Zhan-Kui Jin2, Cui-Xiang Xu3, Qian-Li Dang4, Li-Jie Zhang1, Hong-Nan Chen5, Yao-Jun Song1, Jiang-Cun Yang1. 1. Department of Transfusion Medicine, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an, China. 2. The Second Department of Orthopaedics, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an, China. 3. Department of Shaanxi Provincial Center for Clinical Laboratory, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an, China. 4. Department of Dermatology, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an, China. 5. Department of Laboratory, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an, China.
Abstract
OBJECTIVE: This study aims to learn about the current situation of surgical massive blood transfusion of different surgical departments in China's Tertiary hospitals, which could provide the basis for the formulation of guidelines on massive blood transfusion. METHOD: A multicenter retrospective research on the application status of blood constituents during massive blood transfusion was conducted and a comparative analyses of survival and length of hospitalization in patients from different departments (trauma, cardiac surgery, obstetric conditions, or other common surgeries), were performed. RESULT: In China, during massive blood transfusion the ratio of the dosage of fresh frozen plasma to the dosage of red blood cell suspension reached 1:1-2, while the dosage of platelet and cryoprecipitate appeared to be very small. The risk of in-hospital death were associated with the primary disease in patients receiving massive blood transfusion (Log-Rank P = 0.000), cardiac surgery and trauma patients who received massive blood transfusion have a higher risk of death rate. CONCLUSIONS: Patients undergoing massive blood transfusion among different surgical departments have a certain difference in use of blood transfusion, mortality rate and the time of death. Our findings suggested that we should set up an independent transfusion program in cardiac surgery and trauma patients of massive blood transfusion.
OBJECTIVE: This study aims to learn about the current situation of surgical massive blood transfusion of different surgical departments in China's Tertiary hospitals, which could provide the basis for the formulation of guidelines on massive blood transfusion. METHOD: A multicenter retrospective research on the application status of blood constituents during massive blood transfusion was conducted and a comparative analyses of survival and length of hospitalization in patients from different departments (trauma, cardiac surgery, obstetric conditions, or other common surgeries), were performed. RESULT: In China, during massive blood transfusion the ratio of the dosage of fresh frozen plasma to the dosage of red blood cell suspension reached 1:1-2, while the dosage of platelet and cryoprecipitate appeared to be very small. The risk of in-hospital death were associated with the primary disease in patients receiving massive blood transfusion (Log-Rank P = 0.000), cardiac surgery and traumapatients who received massive blood transfusion have a higher risk of death rate. CONCLUSIONS:Patients undergoing massive blood transfusion among different surgical departments have a certain difference in use of blood transfusion, mortality rate and the time of death. Our findings suggested that we should set up an independent transfusion program in cardiac surgery and traumapatients of massive blood transfusion.
Entities:
Keywords:
Massive transfusion; blood constituents; retrospective analysis; surgical department
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