AIMS: At present there exists no direct comparative data for the detection of in-stent tissue coverage as assessed by intravascular ultrasound (IVUS) and optical coherence tomography (OCT) in clinical settings. To explore this subject, we investigated the correlation between the IVUS and OCT measurements derived from a contemporary population. METHODS AND RESULTS: The present study includes 20 patients who had stents imaged at a six months follow-up with both IVUS and OCT, acquired with an automated pull-back. Off-line analyses were done by an independent validated Core-Lab (RHR, Rome, Italy). Measurements of stent length obtained by IVUS and OCT were 16.3+/-3.0 mm and 16.2+/-3.8 mm respectively (p=0.82) and were similar to nominal length (16.3+/-3.3 mm). Luminal area in the OCT image set was lower than that obtained in the corresponding IVUS image set (3.83+/-1.60 mm2 vs 4.05+/-1.44 mm2, p<0.001), while stent area was significantly higher when measured by OCT (6.61+/-1.39 mm2 vs 6.17+/-1.07 mm2, p<0.001). The percentage of tissue coverage measured by IVUS was lower than that measured in the corresponding OCT image sets (35.5+/-16.4% vs 43.4+/-16.1%, p<0.001). Correlation coefficients were high for repeated OCT measurements by two different observers (r=0.99). CONCLUSIONS: OCT can quantify in-stent coverage and detect strut healing with high reproducibility. IVUS tends to underestimate the percentage of in-stent tissue coverage as compared to OCT.
AIMS: At present there exists no direct comparative data for the detection of in-stent tissue coverage as assessed by intravascular ultrasound (IVUS) and optical coherence tomography (OCT) in clinical settings. To explore this subject, we investigated the correlation between the IVUS and OCT measurements derived from a contemporary population. METHODS AND RESULTS: The present study includes 20 patients who had stents imaged at a six months follow-up with both IVUS and OCT, acquired with an automated pull-back. Off-line analyses were done by an independent validated Core-Lab (RHR, Rome, Italy). Measurements of stent length obtained by IVUS and OCT were 16.3+/-3.0 mm and 16.2+/-3.8 mm respectively (p=0.82) and were similar to nominal length (16.3+/-3.3 mm). Luminal area in the OCT image set was lower than that obtained in the corresponding IVUS image set (3.83+/-1.60 mm2 vs 4.05+/-1.44 mm2, p<0.001), while stent area was significantly higher when measured by OCT (6.61+/-1.39 mm2 vs 6.17+/-1.07 mm2, p<0.001). The percentage of tissue coverage measured by IVUS was lower than that measured in the corresponding OCT image sets (35.5+/-16.4% vs 43.4+/-16.1%, p<0.001). Correlation coefficients were high for repeated OCT measurements by two different observers (r=0.99). CONCLUSIONS: OCT can quantify in-stent coverage and detect strut healing with high reproducibility. IVUS tends to underestimate the percentage of in-stent tissue coverage as compared to OCT.
Authors: Rodolfo Staico; Marco A Costa; Daniel Chamié; Hiram Bezerra; Luciana V Armaganijan; Ricardo A Costa; José Ribamar Costa; Dimytri Siqueira; Marinella Centemero; Áurea Chaves; Luiz Fernando Tanajura; Alexandre Abizaid; Fausto Feres; J Eduardo M R Sousa; Amanda G M R Sousa Journal: Int J Cardiovasc Imaging Date: 2013-03-03 Impact factor: 2.357
Authors: Francesco Prati; Giulio Guagliumi; Gary S Mintz; Marco Costa; Evelyn Regar; Takashi Akasaka; Peter Barlis; Guillermo J Tearney; Ik-Kyung Jang; Elosia Arbustini; Hiram G Bezerra; Yukio Ozaki; Nico Bruining; Darius Dudek; Maria Radu; Andrejs Erglis; Pascale Motreff; Fernando Alfonso; Kostas Toutouzas; Nieves Gonzalo; Corrado Tamburino; Tom Adriaenssens; Fausto Pinto; Patrick W J Serruys; Carlo Di Mario Journal: Eur Heart J Date: 2012-05-31 Impact factor: 29.983
Authors: Ingibjorg Gudmundsdottir; Philip Adamson; Calum Gray; James C Spratt; Miles W Behan; Peter Henriksen; David E Newby; Nicholas Mills; Neal G Uren; Nicholas L Cruden Journal: Open Heart Date: 2015-12-22
Authors: Hong Lu; Juhwan Lee; Martin Jakl; Zhao Wang; Pavel Cervinka; Hiram G Bezerra; David L Wilson Journal: Sci Rep Date: 2020-02-07 Impact factor: 4.379