Literature DB >> 20136305

The "weighted ensemble" path sampling method is statistically exact for a broad class of stochastic processes and binning procedures.

Bin W Zhang1, David Jasnow, Daniel M Zuckerman.   

Abstract

The "weighted ensemble" method, introduced by Huber and Kim [Biophys. J. 70, 97 (1996)], is one of a handful of rigorous approaches to path sampling of rare events. Expanding earlier discussions, we show that the technique is statistically exact for a wide class of Markovian and non-Markovian dynamics. The derivation is based on standard path-integral (path probability) ideas, but recasts the weighted-ensemble approach as simple "resampling" in path space. Similar reasoning indicates that arbitrary nonstatic binning procedures, which merely guide the resampling process, are also valid. Numerical examples confirm the claims, including the use of bins which can adaptively find the target state in a simple model.

Mesh:

Year:  2010        PMID: 20136305      PMCID: PMC2830257          DOI: 10.1063/1.3306345

Source DB:  PubMed          Journal:  J Chem Phys        ISSN: 0021-9606            Impact factor:   3.488


  17 in total

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Authors:  G A Huber; S Kim
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