Literature DB >> 20135302

Uterus conserving prolapse surgery--what is the chance of missing a malignancy?

Arasee Renganathan1, Robin Edwards, Jonathan R A Duckett.   

Abstract

INTRODUCTION AND HYPOTHESIS: Recently, there has been a move towards uterine preserving surgery in the management of pelvic organ prolapse. The negative implications of such surgery have not been delineated. This study aims to identify the risk of finding an unexpected malignancy in these cases.
METHODS: A database containing details of vaginal hysterectomies performed over a 10-year period was searched. Women who underwent surgery for uterine prolapse were included. Women with other indications for surgery and those who presented with symptoms relating to endometrial or cervical malignancy were excluded. As this is a non-interventional observational study, formal ethical approval was not obtained.
RESULTS: Out of 517 women who underwent a vaginal hysterectomy for prolapse, four cases of endometrial carcinoma were identified giving an incidence of 0.8%.
CONCLUSIONS: Conserving a prolapsed uterus without further investigations runs the risk of missing women with endometrial malignancy.

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Year:  2010        PMID: 20135302     DOI: 10.1007/s00192-010-1101-9

Source DB:  PubMed          Journal:  Int Urogynecol J        ISSN: 0937-3462            Impact factor:   2.894


  6 in total

1.  Is microscopic assessment of macroscopically normal hysterectomy specimens necessary?

Authors:  H A Salmon; J H F Smith; M Balsitis
Journal:  J Clin Pathol       Date:  2002-01       Impact factor: 3.411

2.  Is microscopic examination of hysterectomy specimens removed for clinically benign disease necessary?

Authors:  T Andrews; H Monaghan
Journal:  J Clin Pathol       Date:  2007-08-03       Impact factor: 3.411

3.  Detection of occult endometrial carcinoma.

Authors:  L G Koss
Journal:  J Cell Biochem Suppl       Date:  1995

4.  Is transvaginal ultrasound a worthwhile investigation for women undergoing vaginal hysterectomy?

Authors:  S Srikrishna; D Robinson; L Cardozo; J Yazbek; D Jurkovic
Journal:  J Obstet Gynaecol       Date:  2008-05       Impact factor: 1.246

Review 5.  A thin and regular endometrium on ultrasound is very unlikely in patients with endometrial malignancy.

Authors:  T Van den Bosch; D Van Schoubroeck; E Domali; I Vergote; P Moerman; F Amant; D Timmerman
Journal:  Ultrasound Obstet Gynecol       Date:  2007-06       Impact factor: 7.299

6.  Sacrospinous hysteropexy compared to vaginal hysterectomy as primary surgical treatment for a descensus uteri: effects on urinary symptoms.

Authors:  H J van Brummen; G van de Pol; C I M Aalders; A P M Heintz; C H van der Vaart
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2003-09-23
  6 in total
  15 in total

1.  Radical Hysterectomy for Cervical Cancer in Patients With Uterine Prolapse.

Authors:  Nicolae Bacalbasa; Ioana Halmaciu; Dragos Cretoiu; Cristian Balalau; Camelia Diaconu; Laura Iliescu; Gabriel Gorecki; Ciprian Bolca; Adrian Neacsu; Irina Balescu
Journal:  In Vivo       Date:  2020 Jul-Aug       Impact factor: 2.155

Review 2.  Sacrospinous hysteropexy: review and meta-analysis of outcomes.

Authors:  Shveta Kapoor; Kanapathippillai Sivanesan; Jessica Amy Robertson; Mayooran Veerasingham; Vishal Kapoor
Journal:  Int Urogynecol J       Date:  2017-03-03       Impact factor: 2.894

3.  Surgical management of pelvic organ prolapse and uterine descent in the Netherlands.

Authors:  R J Detollenaere; J den Boon; K B Kluivers; M E Vierhout; H W F van Eijndhoven
Journal:  Int Urogynecol J       Date:  2012-09-22       Impact factor: 2.894

4.  Laparoscopic hysteropexy versus vaginal hysterectomy for the treatment of uterovaginal prolapse: a prospective randomized pilot study.

Authors:  Philip Rahmanou; Natalia Price; Simon R Jackson
Journal:  Int Urogynecol J       Date:  2015-07-04       Impact factor: 2.894

5.  Laparoscopic hysteropexy: 10 years' experience.

Authors:  Helen Jefferis; Natalia Price; Simon Jackson
Journal:  Int Urogynecol J       Date:  2017-01-18       Impact factor: 2.894

6.  Vaginal hysterectomy for uterovaginal prolapse: what is the incidence of concurrent gynecological malignancy?

Authors:  Themos Grigoriadis; Aikaterini Valla; Dimitrios Zacharakis; Athanasios Protopapas; Stavros Athanasiou
Journal:  Int Urogynecol J       Date:  2014-10-08       Impact factor: 2.894

Review 7.  Role of Hysteropexy in the Management of Pelvic Organ Prolapse.

Authors:  Zoe S Gan; Daniel S Roberson; Ariana L Smith
Journal:  Curr Urol Rep       Date:  2022-07-05       Impact factor: 2.862

Review 8.  Prevalence of histological abnormalities in hysterectomy specimens performed for prolapse. A systematic review and meta-analysis.

Authors:  Rachel C Nicholson; Aethele Khunda; Paul Ballard; Jon Rees; Carol McCormick
Journal:  Int Urogynecol J       Date:  2021-06-11       Impact factor: 2.894

9.  Importance of Cervical Elongation Assessment for Laparoscopic Sacrocolpopexy.

Authors:  Mikihisa Onigahara; Shintaro Yanazume; Takashi Ushiwaka; Shinichi Togami; Masaki Kamio; Hiroaki Kobayashi
Journal:  Gynecol Minim Invasive Ther       Date:  2021-04-30

Review 10.  Current Role of Hysterectomy in Pelvic Floor Surgery: Time for Reappraisal? A Review of Current Literature and Expert Discussion.

Authors:  Guenter K Noé; Annelize Barnard; Sven Schiermeier; Michael Anapolski
Journal:  Biomed Res Int       Date:  2021-07-06       Impact factor: 3.411

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