Literature DB >> 20122024

When cancer in older adults is undermanaged: the breast cancer story.

Rebecca A Silliman1.   

Abstract

Age is the most important risk factor for breast cancer; age is also a risk factor for undermanagement of breast cancer. One thousand eight hundred fifty-nine women aged 65 and older with early-stage breast cancer were studied, and it was found that undermanagement is a risk factor for recurrence and for dying of breast cancer. Although conservative treatment is probably warranted in patients with tumors having excellent prognostic characteristics and in women with limited life expectancies, standard treatment is needed for the majority of older women if the disproportionate burden of breast cancer in this age group is to be reduced. Better strategies are needed for identifying those most likely to benefit from standard treatment and from systematic surveillance for recurrence. In this regard, collaboration between oncologists and primary care physicians is essential for achieving high-quality care and outcomes in this vulnerable group of patients.

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Year:  2009        PMID: 20122024      PMCID: PMC2908961          DOI: 10.1111/j.1532-5415.2009.02506.x

Source DB:  PubMed          Journal:  J Am Geriatr Soc        ISSN: 0002-8614            Impact factor:   5.562


  15 in total

1.  Comorbidity measurement in elderly female breast cancer patients with administrative and medical records data.

Authors:  C J Newschaffer; T L Bush; L T Penberthy
Journal:  J Clin Epidemiol       Date:  1997-06       Impact factor: 6.437

2.  A new method of classifying prognostic comorbidity in longitudinal studies: development and validation.

Authors:  M E Charlson; P Pompei; K L Ales; C R MacKenzie
Journal:  J Chronic Dis       Date:  1987

3.  Recurrences and second primary breast cancers in older women with initial early-stage disease.

Authors:  Ann M Geiger; Soe Soe Thwin; Timothy L Lash; Diana S M Buist; Marianne N Prout; Feifei Wei; Terry S Field; Marianne Ulcickas Yood; Floyd J Frost; Shelley M Enger; Rebecca A Silliman
Journal:  Cancer       Date:  2007-03-01       Impact factor: 6.860

4.  Cancer screening in elderly patients: a framework for individualized decision making.

Authors:  L C Walter; K E Covinsky
Journal:  JAMA       Date:  2001-06-06       Impact factor: 56.272

5.  Mortality impact of less-than-standard therapy in older breast cancer patients.

Authors:  Marianne Ulcickas Yood; Cynthia Owusu; Diana S M Buist; Ann M Geiger; Terry S Field; Soe Soe Thwin; Timothy L Lash; Marianne N Prout; Feifei Wei; Virginia P Quinn; Floyd J Frost; Rebecca A Silliman
Journal:  J Am Coll Surg       Date:  2007-10-03       Impact factor: 6.113

Review 6.  Older female cancer patients: importance, causes, and consequences of undertreatment.

Authors:  Christine Bouchardy; Elisabetta Rapiti; Stina Blagojevic; Anne-Thérèse Vlastos; Georges Vlastos
Journal:  J Clin Oncol       Date:  2007-05-10       Impact factor: 44.544

7.  Predictors of tamoxifen discontinuation among older women with estrogen receptor-positive breast cancer.

Authors:  Cynthia Owusu; Diana S M Buist; Terry S Field; Timothy L Lash; Soe Soe Thwin; Ann M Geiger; Virginia P Quinn; Floyd Frost; Marianne Prout; Marianne Ulcickas Yood; Feifei Wei; Rebecca A Silliman
Journal:  J Clin Oncol       Date:  2007-12-10       Impact factor: 44.544

8.  Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer.

Authors:  Kevin S Hughes; Lauren A Schnaper; Donald Berry; Constance Cirrincione; Beryl McCormick; Brenda Shank; Judith Wheeler; Lorraine A Champion; Thomas J Smith; Barbara L Smith; Charles Shapiro; Hyman B Muss; Eric Winer; Clifford Hudis; William Wood; David Sugarbaker; I Craig Henderson; Larry Norton
Journal:  N Engl J Med       Date:  2004-09-02       Impact factor: 91.245

9.  Under utilization of surveillance mammography among older breast cancer survivors.

Authors:  Terry S Field; Chyke Doubeni; Matthew P Fox; Diana S M Buist; Feifei Wei; Ann M Geiger; Virginia P Quinn; Timothy L Lash; Marianne N Prout; Marianne Ulcickas Yood; Floyd J Frost; Rebecca A Silliman
Journal:  J Gen Intern Med       Date:  2007-12-01       Impact factor: 5.128

10.  Mammography surveillance and mortality in older breast cancer survivors.

Authors:  Timothy L Lash; Matthew P Fox; Diana S M Buist; Feifei Wei; Terry S Field; Floyd J Frost; Ann M Geiger; Virginia P Quinn; Marianne Ulcickas Yood; Rebecca A Silliman
Journal:  J Clin Oncol       Date:  2007-06-04       Impact factor: 44.544

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  3 in total

1.  Adopting Guidelines into Clinical Practice: Implementation of Trastuzumab in the Adjuvant Treatment of Breast Cancer in Lower Saxony, Germany, in 2007.

Authors:  Clemens Liebrich; Günter Unger; Birgit Dlugosch; Stefan Hofmann; Karl U Petry
Journal:  Breast Care (Basel)       Date:  2011-01-31       Impact factor: 2.860

Review 2.  Prognostic factors in elderly patients with breast cancer.

Authors:  Alessandro Cappellani; Maria Di Vita; Antonio Zanghì; Andrea Cavallaro; Gaetano Piccolo; Marcello Majorana; Giuseppina Barbera; Massimiliano Berretta
Journal:  BMC Surg       Date:  2013-10-08       Impact factor: 2.102

Review 3.  Older breast cancer undertreatment: unconscious bias to undertreat-potential role for the international geriatric radiotherapy group?

Authors:  Nam P Nguyen; Ulf Karlsson; Eromosele Oboite; Julio Alvarenga; Juan Godinez; Alice Zamagni; Micaela Motta; Satya Bose; Vincent Vinh-Hung
Journal:  Transl Cancer Res       Date:  2020-01       Impact factor: 1.241

  3 in total

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