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Literature DB >> 20118997

Cohesin and Cdk1: an anaphase barricade.

Abstract

Separation of sister chromatids at anaphase in metazoan cells requires only the cleavage of the kleisin subunit of centromeric cohesin, but efficient poleward movement of separated sisters requires the associated loss in Cdk1 activity. Activation of the anaphase-promoting complex/cyclosome ensures these events are coordinated.

Entities: Gene

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Year: 2010 PMID： 20118997 DOI： 10.1038/ncb0210-106

Source DB: PubMed Journal: Nat Cell Biol ISSN： 1465-7392 Impact factor: 28.824

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References

16 in total

1. Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast.

Authors: F Uhlmann; D Wernic; M A Poupart; E V Koonin; K Nasmyth
Journal: Cell Date: 2000-10-27 Impact factor: 41.582

2. The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase.

Authors: Izabela Sumara; Elisabeth Vorlaufer; P Todd Stukenberg; Olaf Kelm; Norbert Redemann; Erich A Nigg; Jan-Michael Peters
Journal: Mol Cell Date: 2002-03 Impact factor: 17.970

3. Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis.

Authors: Ana Losada; Michiko Hirano; Tatsuya Hirano
Journal: Genes Dev Date: 2002-12-01 Impact factor: 11.361

4. Wapl controls the dynamic association of cohesin with chromatin.

Authors: Stephanie Kueng; Björn Hegemann; Beate H Peters; Jesse J Lipp; Alexander Schleiffer; Karl Mechtler; Jan-Michael Peters
Journal: Cell Date: 2006-11-16 Impact factor: 41.582

Review 5. Clearing the way for mitosis: is cohesin a target?

Authors: Mitsuhiro Yanagida
Journal: Nat Rev Mol Cell Biol Date: 2009-06-03 Impact factor: 94.444

Review 6. Cohesin: its roles and mechanisms.

Authors: Kim Nasmyth; Christian H Haering
Journal: Annu Rev Genet Date: 2009 Impact factor: 16.830

Cohesin and Cdk1: an anaphase barricade.

1. Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast.

2. The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase.

3. Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis.

4. Wapl controls the dynamic association of cohesin with chromatin.

Review 5. Clearing the way for mitosis: is cohesin a target?

Review 6. Cohesin: its roles and mechanisms.

7. Shugoshin collaborates with protein phosphatase 2A to protect cohesin.

8. Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates.

Review 9. The spindle-assembly checkpoint in space and time.

10. Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei.