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Literature DB >> 19491928

Clearing the way for mitosis: is cohesin a target?

Abstract

In interphase, chromosomes are associated with proteins and RNAs that participate in many processes, such as DNA replication, transcription, recombination and repair of DNA damage. These components (for example, cohesin) might have to be removed during mitosis, as they might become obstacles that inhibit chromosome segregation or reduce its fidelity. Such a clearing mechanism that operates along mitotic chromosomes might require proteins that are implicated in chromosome segregation. I propose that condensin and DNA topoisomerase II (TOP2), as well as separase, help to clear the way for mitosis.

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Year: 2009 PMID： 19491928 DOI： 10.1038/nrm2712

Source DB: PubMed Journal: Nat Rev Mol Cell Biol ISSN： 1471-0072 Impact factor: 94.444

64 in total

Review 1. Adherin: key to the cohesin ring and cornelia de Lange syndrome.

Authors: Dale Dorsett
Journal: Curr Biol Date: 2004-10-05 Impact factor: 10.834

Review 2. The structure and function of SMC and kleisin complexes.

Authors: Kim Nasmyth; Christian H Haering
Journal: Annu Rev Biochem Date: 2005 Impact factor: 23.643

3. Cohesin complex promotes transcriptional termination between convergent genes in S. pombe.

Authors: Monika Gullerova; Nick J Proudfoot
Journal: Cell Date: 2008-03-21 Impact factor: 41.582

Review 4. The regulation of sister chromatid cohesion.

Authors: Ana Losada
Journal: Biochim Biophys Acta Date: 2008-04-24

5. DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe.

Authors: T Uemura; H Ohkura; Y Adachi; K Morino; K Shiozaki; M Yanagida
Journal: Cell Date: 1987-09-11 Impact factor: 41.582

6. Cut1 is loaded onto the spindle by binding to Cut2 and promotes anaphase spindle movement upon Cut2 proteolysis.

Authors: K Kumada; T Nakamura; K Nagao; H Funabiki; T Nakagawa; M Yanagida
Journal: Curr Biol Date: 1998-05-21 Impact factor: 10.834

Review 7. The spindle-assembly checkpoint in space and time.

Authors: Andrea Musacchio; Edward D Salmon
Journal: Nat Rev Mol Cell Biol Date: 2007-04-11 Impact factor: 94.444

8. Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis.

Authors: R Giet; D M Glover
Journal: J Cell Biol Date: 2001-02-19 Impact factor: 10.539

9. Cohesin relocation from sites of chromosomal loading to places of convergent transcription.

Authors: Armelle Lengronne; Yuki Katou; Saori Mori; Shihori Yokobayashi; Gavin P Kelly; Takehiko Itoh; Yoshinori Watanabe; Katsuhiko Shirahige; Frank Uhlmann
Journal: Nature Date: 2004-06-30 Impact factor: 49.962

10. Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization.

Authors: T Uemura; M Yanagida
Journal: EMBO J Date: 1984-08 Impact factor: 11.598

36 in total

Clearing the way for mitosis: is cohesin a target?

Review 1. Adherin: key to the cohesin ring and cornelia de Lange syndrome.

Review 2. The structure and function of SMC and kleisin complexes.

3. Cohesin complex promotes transcriptional termination between convergent genes in S. pombe.

Review 4. The regulation of sister chromatid cohesion.

5. DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe.

6. Cut1 is loaded onto the spindle by binding to Cut2 and promotes anaphase spindle movement upon Cut2 proteolysis.

Review 7. The spindle-assembly checkpoint in space and time.

8. Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis.

9. Cohesin relocation from sites of chromosomal loading to places of convergent transcription.

10. Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization.

1. Cohesin and Cdk1: an anaphase barricade.

2. MCM-BP regulates unloading of the MCM2-7 helicase in late S phase.

3. Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes.

4. DNA replication: Cohesin on the fork.

5. BMI1 suffers a degrading experience.

Review 6. Condensin, master organizer of the genome.

Review 7. Condensins: universal organizers of chromosomes with diverse functions.

8. Influence of the human cohesion establishment factor Ctf4/AND-1 on DNA replication.

9. Condensins promote chromosome recoiling during early anaphase to complete sister chromatid separation.

10. Cohesin's dual role in the DNA damage response: repair and checkpoint activation.